Protein Information

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UniProt AC / UniProt ID P28482 / MK01_HUMAN
Protein Name Mitogen-activated protein kinase 1
Gene Name Name: MAPK1
Synonyms:ERK2,PRKM1,PRKM2;
Organism Homo sapiens (Human)

PRO ID PR:P28482
DAG View
PRO Name mitogen-activated protein kinase 1 (human)
Definition A mitogen-activated protein kinase 1 that is encoded in the genome of human.
Short Label hMAPK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P28482 (MAPK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 12665801, ...22223895
Y25 Phosphorylation PhosphoSitePlus
S29 Phosphorylation O00141 (SGK1) neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 19447520
Y36 Phosphorylation PhosphoSitePlus   RLIMS-P 30905967
Y43 Phosphorylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
T63 Phosphorylation PhosphoSitePlus
C65 S-Nitrosylation dbSNO 19483679
K99 Ubiquitination PhosphoSitePlus
Y113 Phosphorylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
C166 S-Nitrosylation dbSNO 19483679
T181 Phosphorylation PhosphoSitePlus
T185 Phosphorylation Q02750 (MAP2K1) , P36507 (MAP2K2) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 28380434, 17192257, 32188029, ...8226933, 25818999, 21406692, 23186163, 21768338, 24735981, 22529914, 21251217, 21365009, 33836754, 27281782, 21336309, 15935618, 11971971, 9677429, 9166761, 19690332, 18669648
Y187 Phosphorylation P28482 (MAPK1) , Q02750 (MAP2K1) , P07949 (RET) , O60674 (JAK2) , P36507 (MAP2K2) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 28380434, 15972258, 19053285, ...17192257, 11971971, 23286773, 32188029, 8226933, 25818999, 21406692, 23186163, 21768338, 1378617, 24735981, 22529914, 21251217, 21365009, 27083547, 16464493, 33836754, 27281782, 19494114, 21336309, 15935618, 15592455, 9677429, 16094384, 1835084, 19690332, 18083107, 18669648, 16153436
T190 Phosphorylation P28482 (MAPK1) neXtProt   PhosphoSitePlus   UniProt 19060905
Y193 Phosphorylation PhosphoSitePlus   RLIMS-P 31196894
R194 Methylation PhosphoSitePlus
S202 Phosphorylation IntAct   PhosphoSitePlus 23560844
K203 Ubiquitination PhosphoSitePlus
G204 Phosphorylation IntAct 23560844
Y205 Phosphorylation phospho.ELM   PhosphoSitePlus 9124279
T206 Phosphorylation PhosphoSitePlus
S246 Phosphorylation P68400 (CSNK2A1) , P28482 (MAPK1) PhosphoSitePlus   UniProt 18760948, 21730285
S248 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   UniProt 18760948, 21730285
K259 Ubiquitination PhosphoSitePlus
Y263 Phosphorylation PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus   UniProt 19369195
K285 Ubiquitination PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
T295 Phosphorylation PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
Y316 Phosphorylation RLIMS-P 21034601
K330 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S29 Phosphorylation P04049 (RAF1) HPRD 15664191
S41 Phosphorylation P28482 (MAPK1) HPRD 1378617
T181 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231
T185 Phosphorylation P28482 (MAPK1) HPRD   PRO 19901323, 17389395, 91184134, ...1378617, 18691976, 1712480, 19651622, 18669648, 19415658, 20068231
Y187 Phosphorylation P28482 (MAPK1) , P07949 (RET) , Q02750 (MAP2K1) HPRD   PRO 17016520, 18578522, 17389395, ...18691976, 18452278, 19651622, 18669648, 16153436, 18707149, 19901323, 19415658, 20068231, 16497976
T190 Phosphorylation HPRD 20068231
S202 Phosphorylation HPRD 18691976
Y205 Phosphorylation HPRD 15466214


P28482 (MAPK1) as PTM Enzyme



Substrate Site Score Source PMID
C9JLW8 (MCRIP1) S21 PhosphoSitePlus   Signor 25728771
C9JLW8 (MCRIP1) T30 neXtProt   PhosphoSitePlus   Signor 22028470, 25728771
O00213 (APBB1) S175 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 14697653
O00213 (APBB1) S287 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 14697653
O00213 (APBB1) S347 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 14697653
O00213 (APBB1) T709 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 14697653
O00267 (SUPT5H) S666 neXtProt 22028470
O00429 (DNM1L) S616 neXtProt   PhosphoSitePlus 25658204, 25658205
O00562 (PITPNM1) T794 phospho.ELM   PhosphoSitePlus   Signor 15125835
O00562 (PITPNM1) T1223 phospho.ELM   PhosphoSitePlus   Signor 15125835
O14613 (CDC42EP2) S101 neXtProt 22028470
O43251 (RBFOX2) T7 neXtProt 22028470
O43294 (TGFB1I1) S141 neXtProt 22028470
O43521 (BCL2L11) S69 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 17525735, 15486195, 14555991
O43524 (FOXO3) S294 neXtProt   PhosphoSitePlus   Signor 18204439, 22128155
O43524 (FOXO3) S344 neXtProt   PhosphoSitePlus   Signor 18204439, 22128155
O43524 (FOXO3) S425 neXtProt   PhosphoSitePlus   Signor 18204439, 22128155
O43623 (SNAI2) S87 PhosphoSitePlus 25855378
O43623 (SNAI2) S104 PhosphoSitePlus 25855378
O60331 (PIP5K1C) S650 neXtProt 15738269
O60502 (OGA) T709 neXtProt 22028470
O60504-2 (SORBS3) S188 neXtProt   PhosphoSitePlus 15184391
O60504 (SORBS3) S530 Signor 15184391
O60504 (SORBS3) T585 neXtProt 22028470
O60749 (SNX2) T104 neXtProt 22028470
O75030-9 (MITF) S73 neXtProt   PhosphoSitePlus 20701798, 16246839, 9440696
O75030 (MITF) S180 Signor 10673502
O75151 (PHF2) S655 neXtProt 22028470
O75581 (LRP6) S1490 PhosphoSitePlus 22558232
O75581 (LRP6) T1572 PhosphoSitePlus 22558232
O75582 (RPS6KA5) S360 phospho.ELM   PhosphoSitePlus   Signor 11940578, 15568999, 9687510
O75582-2 (RPS6KA5) S376 HPRD 19651622, 11994045, 20068231
O75582 (RPS6KA5) T581 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 11994045, 17117922, 15568999, ...18267068, 11940578
O75582 (RPS6KA5) T700 neXtProt 17117922
O94804 (STK10) T952 neXtProt 22028470
O94811 (TPPP) T14 neXtProt 17693641
O94811 (TPPP) S18 neXtProt   PhosphoSitePlus 17693641
O94811 (TPPP) S160 neXtProt   PhosphoSitePlus 17693641
O95785 (WIZ) S983 neXtProt 22028470
O95863 (SNAI1) S82 PhosphoSitePlus 23644467
O95863 (SNAI1) S104 PhosphoSitePlus 23644467
O95997 (PTTG1) S165 Signor 10906323
P00533 (EGFR) T693 neXtProt   phospho.ELM   PhosphoSitePlus 1939237, 1651322
P01100-1 (FOS) T232 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 7816602
P01100 (FOS) T325 HPRD   neXtProt   Signor 12134156, 12972619
P01100-1 (FOS) T331 HPRD   neXtProt   Signor 12134156, 12972619
P01100-1 (FOS) S374 HPRD   neXtProt   Signor 8248197, 12134156, 12972619, ...20068231, 18452278
P01106 (MYC) T58 neXtProt   PhosphoSitePlus 10551811
P01106 (MYC) S62 neXtProt   phospho.ELM   PhosphoSitePlus 10551811, 1651323
P01106 (MYC) S71 neXtProt 10551811
P02545 (LMNA) S22 neXtProt 1555589, 22028470
P02686-5 (MBP) T99 HPRD 15380617
P02686 (MBP) T229 HPRD   Signor 12760422
P02686 (MBP) T232 HPRD   phospho.ELM   PhosphoSitePlus   Signor 1939237, 12760422, 16401070
P03372 (ESR1) S104 neXtProt   PhosphoSitePlus   Signor 17615152, 18372406, 12118371
P03372 (ESR1) S106 neXtProt   PhosphoSitePlus   Signor 12118371, 18372406, 17615152
P03372 (ESR1) S118 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 15059947, 7491495, 12093745, ...9528769, 17615152, 18372406, 12118371, 15919818, 10409727, 12466266
P04049 (RAF1) S29 HPRD   neXtProt 18691976, 15664191
P04049-1 (RAF1) S289 HPRD   neXtProt 18691976, 15664191
P04049 (RAF1) S296 HPRD   neXtProt 19651622, 15664191, 20068231
P04049 (RAF1) S301 HPRD   neXtProt 18691976, 15664191, 20068231
P04049 (RAF1) S642 HPRD   neXtProt 18767875, 18669648, 15664191
P04150-1 (NR3C1) S226 HPRD   neXtProt 18669648, 9199329, 12351702
P04637 (TP53) S15 HPRD   neXtProt   PhosphoSitePlus 10781582, 12955074, 12091386, ...10958792, 14965474, 11896587
P04637-1 (TP53) T55 HPRD   neXtProt   PhosphoSitePlus 11409876, 15116093
P05023 (ATP1A1) S16 neXtProt 14976217
P05198 (EIF2S1) S52 neXtProt   PhosphoSitePlus 17404396
P05787-1 (KRT8) S74 HPRD 9211903, 18691976, 11788583, ...19007248, 11781324
P05787 (KRT8) T431 neXtProt 9054461
P06239 (LCK) S42 phospho.ELM   Signor 8226850, 8506364
P06239 (LCK) S59 HPRD   neXtProt   PhosphoSitePlus   Signor 8618896, 8506364
P06401 (PGR) S294 phospho.ELM   PhosphoSitePlus   Signor 17717077, 10655479, 12529413
P07101-3 (TH) S31 PhosphoSitePlus 16644734, 12421349
P07101-2 (TH) S58 PhosphoSitePlus 16644734
P07101 (TH) S62 neXtProt   PhosphoSitePlus   Signor 7901013, 16644734, 1347949, ...11359875
P07196 (NEFL) T21 PhosphoSitePlus 16452125
P08047 (SP1) S59 neXtProt   PhosphoSitePlus   Signor 19318349, 11904305
P08047 (SP1) T453 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P+   Signor 19318349, 14593115, 20882567, ...11904305
P08047-1 (SP1) T739 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P+   Signor 19318349, 14593115, 20882567, ...11904305
P09874 (PARP1) S372 PhosphoSitePlus   Signor 16627622
P09874 (PARP1) T373 PhosphoSitePlus   Signor 16627622
P09917 (ALOX5) S272 Signor 12670876
P09917 (ALOX5) S664 neXtProt   PhosphoSitePlus   Signor 12205041, 12670876
P10070 (GLI2) T903 neXtProt 22028470
P10242-1 (MYB) S532 HPRD 19651622, 8960373
P10275 (AR) S516 HPRD   PhosphoSitePlus   Signor 10318905, 18511414
P10415 (BCL2) T56 PhosphoSitePlus   Signor 10669763
P10415 (BCL2) S70 neXtProt   Signor 10669763, 10677502
P10415 (BCL2) T74 PhosphoSitePlus   Signor 10669763
P10415 (BCL2) S87 HPRD   neXtProt   PhosphoSitePlus   Signor 15225643, 10669763, 23272207, ...10567572, 12039864
P10636-8 (MAPT) S46 PhosphoSitePlus 9614189
P10636-8 (MAPT) T50 PhosphoSitePlus 9614189
P10636-6 (MAPT) T117 HPRD 9832145, 10737616
P10636-6 (MAPT) T123 HPRD 11181841, 7566346, 9771888, ...9832145, 18510355, 9199504
P10636-6 (MAPT) S144 HPRD 19413330, 9771888, 7566346, ...12226093, 1330687, 12387894, 19415658, 9565682, 9832145, 9199504
P10636-8 (MAPT) T153 neXtProt   PhosphoSitePlus 9614189
P10636-8 (MAPT) T175 HPRD   PhosphoSitePlus 9832145, 9614189, 10737616
P10636-8 (MAPT) T181 PhosphoSitePlus 9614189, 12801934
P10636-8 (MAPT) S199 PhosphoSitePlus 9614189
P10636-8 (MAPT) S202 HPRD   neXtProt   PhosphoSitePlus 19413330, 12801934, 9771888, ...7566346, 12226093, 1330687, 12387894, 19415658, 9565682, 9832145, 9614189, 9199504
P10636-8 (MAPT) T205 neXtProt   PhosphoSitePlus 9614189
P10636-8 (MAPT) T212 neXtProt   PhosphoSitePlus 9614189
P10636-8 (MAPT) T217 PhosphoSitePlus 9614189
P10636-8 (MAPT) T231 neXtProt 9614189
P10636-8 (MAPT) S235 neXtProt   PhosphoSitePlus 9614189
P10636-8 (MAPT) S396 PhosphoSitePlus 9614189
P10636-8 (MAPT) S404 neXtProt   PhosphoSitePlus 9614189
P10636-8 (MAPT) S422 PhosphoSitePlus 9614189
P10636 (MAPT) S519 Signor 10737616
P10636 (MAPT) T522 Signor 10737616
P10636 (MAPT) S721 Signor 10737616
P10646 (TFPI) S202 neXtProt 22028470
P10828 (THRB) S142 phospho.ELM   PhosphoSitePlus   Signor 12809513
P11362 (FGFR1) S777 neXtProt   PhosphoSitePlus   Signor 23405013
P11388 (TOP2A) S1213 phospho.ELM   PhosphoSitePlus 7635160
P11388 (TOP2A) S1247 phospho.ELM   PhosphoSitePlus 7635160
P11388 (TOP2A) S1354 phospho.ELM   PhosphoSitePlus 7635160
P11388 (TOP2A) S1361 phospho.ELM   PhosphoSitePlus 7635160
P11388 (TOP2A) S1393 phospho.ELM   PhosphoSitePlus 7635160
P12036 (NEFH) S518 HPRD 18510355, 9592082
P12036 (NEFH) S526 HPRD 9592082
P12036 (NEFH) S532 HPRD 9592082
P12270 (TPR) T2116 neXtProt   Signor 22028470, 18794356, 12594221
P12270 (TPR) T2137 neXtProt   Signor 22028470, 18794356, 12594221
P12270 (TPR) S2155 neXtProt   Signor 22028470, 18794356, 12594221
P12270 (TPR) T2214 Signor 18794356
P12980 (LYL1) S36 neXtProt   PhosphoSitePlus 20844761
P14543 (NID1) S333 neXtProt 22028470
P14598 (NCF1) S345 neXtProt   PhosphoSitePlus   Signor 8626435, 16778989
P14598 (NCF1) S348 neXtProt 8626435
P14618 (PKM) S37 PhosphoSitePlus 23178880
P14635 (CCNB1) S126 neXtProt   PhosphoSitePlus 12447691
P14635 (CCNB1) S128 neXtProt   PhosphoSitePlus 12447691
P14784 (IL2RB) T476 PhosphoSitePlus 26152718
P14921 (ETS1) T38 neXtProt   PhosphoSitePlus 20361728, 8761310
P15036 (ETS2) T72 neXtProt 11027273
P15056 (BRAF) S151 RLIMS-P+   Signor 21478863
P15056 (BRAF) T401 PhosphoSitePlus 21135229
P15056 (BRAF) S750 neXtProt 14654779
P15056 (BRAF) T753 neXtProt   PhosphoSitePlus 16508002, 14654779
P15336 (ATF2) T69 Signor 20068231
P15336 (ATF2) T71 neXtProt   PhosphoSitePlus   Signor 12110590
P15336 (ATF2) S90 PhosphoSitePlus 15304344
P15391-1 (CD19) Y348 HPRD 10706702, 16497976
P15391-1 (CD19) Y378 HPRD 10706702
P15391-1 (CD19) Y409 HPRD 10706702
P15391-1 (CD19) Y439 HPRD 10706702
P15923-2 (TCF3) S352 neXtProt   PhosphoSitePlus 12810726
P15923-2 (TCF3) T355 HPRD   neXtProt   PhosphoSitePlus 12810726, 14592976
P15923-2 (TCF3) S359 neXtProt   PhosphoSitePlus 12810726
P16949 (STMN1) S25 neXtProt 22028470
P16949 (STMN1) S38 neXtProt   Signor 20630875, 22028470
P17252 (PRKCA) T638 neXtProt 20513439
P17302 (GJA1) S255 HPRD   neXtProt   Signor 22028470, 19664994, 9535909, ...12637502, 8631994
P17302 (GJA1) S279 Signor 9535909
P17302 (GJA1) S282 HPRD   Signor 9535905, 9535909, 12637502, ...8631994
P17480 (UBTF) T117 HPRD   neXtProt   phospho.ELM   Signor 11741541
P17480 (UBTF) T201 HPRD   neXtProt   phospho.ELM   Signor 18669648, 11741541, 19007248, ...20068231
P17535 (JUND) S100 Signor 22327296
P17655 (CAPN2) S50 phospho.ELM   PhosphoSitePlus   Signor 14993287
P17676-1 (CEBPB) T235 HPRD   PhosphoSitePlus   Signor 19413330, 8384717, 19723873
P17861 (XBP1) S68 PhosphoSitePlus 23277279
P17861 (XBP1) S181 PhosphoSitePlus 23277279
P19419 (ELK1) S383 HPRD   neXtProt   PhosphoSitePlus 15782123, 12947314, 8262053, ...20675591
P19419 (ELK1) S389 neXtProt 8262053
P19438-1 (TNFRSF1A) S274 HPRD 11606045
P19438-1 (TNFRSF1A) T280 HPRD 11606045
P19484 (TFEB) S142 Signor 21617040
P19525 (EIF2AK2) T451 neXtProt   PhosphoSitePlus   Signor 17404396, 9528799
P19634 (SLC9A1) S693 HPRD   PhosphoSitePlus 18669648, 20068231, 15253667
P19634-1 (SLC9A1) S766 HPRD 15253667
P19634 (SLC9A1) S770 HPRD   PhosphoSitePlus   Signor 17209041, 18669648, 15253667
P19634-1 (SLC9A1) T779 HPRD 15253667
P19634 (SLC9A1) S785 HPRD   PhosphoSitePlus 18088087, 18669648, 20058876, ...19415658, 15253667
P19793 (RXRA) T82 Signor 17604322
P19793 (RXRA) S260 HPRD   phospho.ELM   PhosphoSitePlus   Signor 11826406, 17604322, 12048211, ...10377179
P19878 (NCF2) T233 PhosphoSitePlus 9931304
P22736-1 (NR4A1) T143 HPRD 11883936
P22736 (NR4A1) S431 PhosphoSitePlus 22002310
P23396 (RPS3) T42 phospho.ELM   PhosphoSitePlus   Signor 15950189, 17560175
P23396 (RPS3) T221 neXtProt 22028470
P23443 (RPS6KB1) S434 neXtProt   PhosphoSitePlus   Signor 14967450, 11279232, 19085255, ...21035469, 7545671, 11872747
P23443 (RPS6KB1) T444 PhosphoSitePlus   Signor 11705993, 15774499, 11872747
P23443 (RPS6KB1) S447 PhosphoSitePlus   Signor 14967450, 19085255, 21035469, ...11872747, 7545671
P24046-1 (GABRR1) T394 HPRD 12175859
P24046-1 (GABRR1) S435 HPRD 12175859
P24046-1 (GABRR1) S440 HPRD 12175859
P24928 (POLR2A) S1619 phospho.ELM   Signor 14662762, 12721286
P24928 (POLR2A) S1626 Signor 14662762
P24928 (POLR2A) S1647 Signor 14662762
P24928 (POLR2A) S1654 Signor 14662762
P24928 (POLR2A) S1668 Signor 14662762
P24928 (POLR2A) S1675 Signor 14662762
P24928 (POLR2A) S1696 Signor 14662762
P24928 (POLR2A) S1717 Signor 14662762
P24928 (POLR2A) S1724 Signor 14662762
P24928 (POLR2A) S1738 Signor 14662762
P24928 (POLR2A) S1766 Signor 14662762
P24928 (POLR2A) S1787 Signor 14662762
P24928 (POLR2A) S1864 Signor 14662762
P24928 (POLR2A) S1871 Signor 14662762
P24928 (POLR2A) S1882 Signor 14662762
P24928 (POLR2A) S1892 Signor 14662762
P24928 (POLR2A) S1899 Signor 14662762
P24928 (POLR2A) S1913 Signor 14662762
P24928 (POLR2A) S1920 Signor 14662762
P24928 (POLR2A) S1927 Signor 14662762
P24928 (POLR2A) S1934 Signor 14662762
P24928 (POLR2A) S1944 Signor 14662762
P24928 (POLR2A) S1951 Signor 14662762
P24941 (CDK2) T160 PhosphoSitePlus   Signor 12359725
P27708 (CAD) T456 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10659854, 14991569, 17206380, ...12438317, 15890648
P28482-1 (MAPK1) S41 HPRD 1378617
P28482-1 (MAPK1) T185 HPRD 19901323, 18691976, 17389395, ...91184134, 1378617, 1712480, 19651622, 18669648, 19415658, 20068231
P28482 (MAPK1) Y187 HPRD   neXtProt 17016520, 18691976, 18578522, ...17389395, 1835084, 18452278, 19651622, 18669648, 16153436, 18707149, 19901323, 19415658, 20068231, 16497976
P28482 (MAPK1) T190 neXtProt   UniProt 19060905
P28482 (MAPK1) S246 PhosphoSitePlus 21730285
P28562 (DUSP1) S296 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 16286470
P28562 (DUSP1) S323 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 16286470
P28562 (DUSP1) S359 HPRD   Signor 10617468
P28562 (DUSP1) S364 Signor 10617468
P29590 (PML) T28 PhosphoSitePlus   Signor 15093545
P29590 (PML) S36 PhosphoSitePlus   Signor 15093545
P29590-4 (PML) S38 PhosphoSitePlus   Signor 15093545
P29590-4 (PML) S40 PhosphoSitePlus   Signor 15093545
P29590-4 (PML) S527 PhosphoSitePlus   Signor 15093545
P29590-4 (PML) S530 PhosphoSitePlus   Signor 15093545
P30041 (PRDX6) T177 PhosphoSitePlus   Signor 19140803
P30307 (CDC25C) S216 RLIMS-P+ 16582626
P31645 (SLC6A4) T616 PhosphoSitePlus 24450286
P31749 (AKT1) S473 RLIMS-P+ 17634416
P31943 (HNRNPH1) S104 neXtProt 22028470
P32004 (L1CAM) S1204 PhosphoSitePlus 10608864
P32004 (L1CAM) S1248 PhosphoSitePlus 10608864
P32121 (ARRB2) S14 PhosphoSitePlus 26324936
P32121 (ARRB2) T276 PhosphoSitePlus 26324936
P33076 (CIITA) S280 neXtProt   PhosphoSitePlus   Signor 17095509, 15210796, 26181363, ...18245089
P33076 (CIITA) S288 neXtProt   PhosphoSitePlus   Signor 15210796, 18245089
P33981 (TTK) S821 PhosphoSitePlus 18787396
P35236 (PTPN7) T66 neXtProt   PhosphoSitePlus 10206983
P35236 (PTPN7) S93 neXtProt   PhosphoSitePlus 10206983
P35236-2 (PTPN7) T105 HPRD 18088087, 10206983
P35236-2 (PTPN7) S132 HPRD 10206983
P35398-4 (RORA) T128 PhosphoSitePlus 17512500
P35398 (RORA) T183 Signor 17512500
P35568 (IRS1) S312 Signor 17242212
P35568 (IRS1) S616 HPRD   neXtProt   Signor 9395471, 15001544, 16131083
P35568 (IRS1) S636 HPRD   neXtProt   PhosphoSitePlus   Signor 19651622, 16131083, 12510059, ...17640984
P35568 (IRS1) S639 neXtProt   PhosphoSitePlus 17640984
P35658 (NUP214) S1710 PhosphoSitePlus 19767751
P35658 (NUP214) S1809 PhosphoSitePlus 19767751
P36956-3 (SREBF1) T81 PhosphoSitePlus 25353341
P36956-3 (SREBF1) S93 PhosphoSitePlus 25353341
P36956 (SREBF1) S117 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10915800, 20863500, 18669648
P36956-4 (SREBF1) S147 HPRD 10915800, 18669648
P37231 (PPARG) S112 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 9030579, 11733495
P37802 (TAGLN2) S145 Signor 30041673
P38936 (CDKN1A) T57 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 19364816
P38936 (CDKN1A) S130 neXtProt   PhosphoSitePlus   Signor 19364816
P40763-2 (STAT3) S726 HPRD 19413330, 18691976, 12763138, ...9343414, 12576423, 20058876, 11350938, 9872331, 10521505, 18669648, 18491316, 14551213, 20068231
P40763-1 (STAT3) S727 HPRD   RLIMS-P+ 19413330, 18691976, 12763138, ...10446219, 12576423, 25584415, 20058876, 11350938, 9872331, 10521505, 18669648, 18491316, 14551213, 20068231, 9343414
P41162 (ETV3) S139 neXtProt 22028470
P41182 (BCL6) S333 neXtProt   PhosphoSitePlus   Signor 9649500
P41182 (BCL6) S343 neXtProt   PhosphoSitePlus   Signor 9649500
P42224 (STAT1) S727 neXtProt 14963018
P42229 (STAT5A) S780 phospho.ELM   PhosphoSitePlus   Signor 10194762
P42702-1 (LIFR) S1044 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 7777512
P43354 (NR4A2) S126 phospho.ELM   Signor 17681692
P43354 (NR4A2) T132 phospho.ELM   Signor 17681692
P43694 (GATA4) S105 neXtProt 11585926
P46527 (CDKN1B) S10 neXtProt   PhosphoSitePlus   Signor 10831586, 11726503
P46527 (CDKN1B) S178 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10831586
P46527 (CDKN1B) T187 neXtProt   PhosphoSitePlus   Signor 10831586, 10931950
P46695 (IER3) T18 HPRD   neXtProt   PhosphoSitePlus   Signor 12356731
P46821 (MAP1B) S1785 neXtProt 22028470
P47712 (PLA2G4A) S505 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 8381049, 9468497
P48634 (PRRC2A) T610 neXtProt 22028470
P48634 (PRRC2A) S1004 neXtProt 22028470
P48634 (PRRC2A) S1219 neXtProt 22028470
P49023-2 (PXN) S83 PhosphoSitePlus 20628053
P49023-2 (PXN) S126 PhosphoSitePlus 20628053
P49023-2 (PXN) S130 PhosphoSitePlus 20628053
P49137 (MAPKAPK2) S9 neXtProt   phospho.ELM   PhosphoSitePlus 8846784
P49137 (MAPKAPK2) T25 neXtProt   PhosphoSitePlus 8846784
P49137 (MAPKAPK2) T222 neXtProt   PhosphoSitePlus   Signor 8846784
P49137 (MAPKAPK2) S272 neXtProt   PhosphoSitePlus   Signor 8846784
P49137 (MAPKAPK2) T334 neXtProt   PhosphoSitePlus   Signor 8846784, 22028470
P49137 (MAPKAPK2) T338 neXtProt 8846784
P49407-2 (ARRB1) S404 HPRD 17322306, 18767875, 19413330, ...20068231, 19651622
P49407 (ARRB1) S412 HPRD   neXtProt   PhosphoSitePlus   Signor 19413330, 17322306, 18767875, ...19153083, 19651622, 15456867, 10347142, 20068231
P49418 (AMPH) S293 Signor 15262992
P49418 (AMPH) S295 Signor 15262992
P49585 (PCYT1A) S315 Signor 15788406
P49715 (CEBPA) S21 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 14701740
P49790 (NUP153) S257 PhosphoSitePlus 19767751
P49790 (NUP153) S320 PhosphoSitePlus 19767751
P49790 (NUP153) S334 PhosphoSitePlus 19767751
P49790 (NUP153) S338 PhosphoSitePlus 19767751
P49790 (NUP153) T369 PhosphoSitePlus 19767751
P49790 (NUP153) T388 PhosphoSitePlus   Signor 19767751
P49790 (NUP153) T413 PhosphoSitePlus 19767751
P49790 (NUP153) S516 PhosphoSitePlus 19767751
P49790 (NUP153) S522 PhosphoSitePlus 19767751
P49790 (NUP153) S529 PhosphoSitePlus   Signor 19767751
P49790 (NUP153) S614 neXtProt 19767751, 22028470
P49795 (RGS19) S151 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10993892, 15488168
P49815-1 (TSC2) S540 HPRD 15851026
P49815-1 (TSC2) S664 HPRD   phospho.ELM   PhosphoSitePlus   Signor 15851026, 17671177
P49841 (GSK3B) T43 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 16039586
P50548 (ERF) S161 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10330152, 18669648
P50548 (ERF) S246 HPRD   neXtProt   PhosphoSitePlus   Signor 10330152
P50548 (ERF) S251 HPRD   neXtProt   PhosphoSitePlus   Signor 10330152
P50548 (ERF) T526 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 22028470, 18212344, 7588608, ...19664994, 10330152, 18669648
P50616 (TOB1) S152 HPRD   neXtProt   PhosphoSitePlus   Signor 12151396, 12050114
P50616 (TOB1) S154 HPRD   neXtProt   PhosphoSitePlus   Signor 20068231, 12151396, 12050114
P50616 (TOB1) S164 HPRD   neXtProt   PhosphoSitePlus   Signor 12050114, 20068231, 12151396
P51168 (SCNN1B) T615 neXtProt 11805112
P51170 (SCNN1G) T622 HPRD   neXtProt 11805112
P51812 (RPS6KA3) S386 neXtProt 10480933
P51812 (RPS6KA3) Y488 PhosphoSitePlus 17785202
P51812 (RPS6KA3) Y529 PhosphoSitePlus 17785202
P52945 (PDX1) S61 neXtProt   PhosphoSitePlus 12810726
P52945 (PDX1) S66 neXtProt   PhosphoSitePlus 12810726
P53355 (DAPK1) S734 HPRD   neXtProt   PhosphoSitePlus   Signor 15616583
P53805 (RCAN1) S167 neXtProt 12063245
P55211 (CASP9) T125 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 12792650, 18669648, 18083711
P61978 (HNRNPK) S284 PhosphoSitePlus 26804170
P68400 (CSNK2A1) T360 neXtProt   PhosphoSitePlus   Signor 19941816
P68400 (CSNK2A1) S362 neXtProt   PhosphoSitePlus   Signor 19941816
P68431 (H3C12) S29 neXtProt 11278789
P78347-2 (GTF2I) S627 PhosphoSitePlus 10648599
P78347-2 (GTF2I) S633 PhosphoSitePlus 10648599
P78347 (GTF2I) S668 Signor 10648599
P78347 (GTF2I) S674 Signor 10648599
P78352 (DLG4) T287 neXtProt 14741046
P78536 (ADAM17) T735 PhosphoSitePlus 18187448
P78559 (MAP1A) T2042 neXtProt 22028470
P78559 (MAP1A) S2419 neXtProt 22028470
P84022 (SMAD3) T179 HPRD   phospho.ELM   PhosphoSitePlus   Signor 10197981, 16156666
P84022 (SMAD3) S204 HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P+   Signor 19914168, 15241418, 10197981, ...19914161, 24080014, 16156666
P84022 (SMAD3) S208 HPRD   phospho.ELM   PhosphoSitePlus   Signor 15241418, 16156666, 10197981, ...19914161, 19914168
P84022-1 (SMAD3) S213 HPRD   phospho.ELM   PhosphoSitePlus   Signor 10197981, 19914161, 19914168
P84243 (H3-3B) S29 Signor 15994958
Q00587 (CDC42EP1) S113 neXtProt 22028470
Q00587 (CDC42EP1) S195 neXtProt 22028470
Q00613 (HSF1) S307 neXtProt 8940068
Q00975 (CACNA1B) S411 neXtProt 16406008
Q00975 (CACNA1B) S446 neXtProt 16406008
Q01196 (RUNX1) S249 Signor 16046550
Q01196 (RUNX1) S266 Signor 16046550
Q01196 (RUNX1) T273 Signor 16046550
Q01196-8 (RUNX1) S276 PhosphoSitePlus   Signor 16046550, 15475366
Q01196-8 (RUNX1) S293 PhosphoSitePlus 15475366
Q01196-8 (RUNX1) T300 PhosphoSitePlus 15475366
Q01196-8 (RUNX1) S303 PhosphoSitePlus 15475366
Q01196-8 (RUNX1) S462 PhosphoSitePlus 15475366
Q01844 (EWSR1) T79 neXtProt   PhosphoSitePlus   Signor 19076070
Q01860 (POU5F1) S111 PhosphoSitePlus   Signor 22474382, 23024368
Q01860 (POU5F1) T118 PhosphoSitePlus 22474382
Q01860 (POU5F1) S355 PhosphoSitePlus 22474382
Q01959 (SLC6A3) S53 neXtProt 19146407
Q02224 (CENPE) S2605 neXtProt   PhosphoSitePlus 9744883
Q02224 (CENPE) S2608 neXtProt   PhosphoSitePlus 9744883
Q02224 (CENPE) S2639 neXtProt   PhosphoSitePlus 9744883
Q02224 (CENPE) S2654 neXtProt   PhosphoSitePlus 9744883
Q02447 (SP3) S73 PhosphoSitePlus   Signor 17685427
Q02641 (CACNB1) S161 neXtProt 16406008
Q02641 (CACNB1) S348 neXtProt 16406008
Q02750 (MAP2K1) T286 PhosphoSitePlus 25971971
Q02750 (MAP2K1) T292 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus 8157000, 25971971, 10567369, ...9351825, 12594221
Q02750 (MAP2K1) T386 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10567369
Q02952 (AKAP12) S286 neXtProt 22028470
Q04206 (RELA) T435 phospho.ELM 15073167
Q04637-8 (EIF4G1) S1232 PhosphoSitePlus 23263986
Q05209 (PTPN12) S571 PhosphoSitePlus 21876001
Q05397 (PTK2) S910 neXtProt   RLIMS-P+ 12692126, 20811717
Q05469-1 (LIPE) T891 HPRD 11581251
Q05682-4 (CALD1) S534 PhosphoSitePlus 26079947
Q05682 (CALD1) S759 Signor 10514499
Q05682 (CALD1) S789 neXtProt   Signor 10514499, 10751321
Q07343-2 (PDE4B) S487 PhosphoSitePlus 11030732
Q07343 (PDE4B) S659 PhosphoSitePlus 11030732
Q07666 (KHDRBS1) S58 HPRD   Signor 18691976, 12478298, 19664995, ...20068231
Q07666 (KHDRBS1) T72 Signor 12478298
Q07666-1 (KHDRBS1) T84 HPRD   Signor 12478298
Q07812 (BAX) T167 RLIMS-P+ 19182807
Q07820 (MCL1) T163 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P+   Signor 25324174, 18676833, 15241487, ...12223490
Q07866 (KLC1) S460 neXtProt   Signor 21385839
Q07869 (PPARA) S12 HPRD   Signor 10187842
Q07869-1 (PPARA) S21 HPRD   Signor 10187842
Q07889 (SOS1) S1132 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus 8816480
Q07889 (SOS1) S1167 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus 8816480
Q07889 (SOS1) S1178 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus 8816480
Q07889 (SOS1) S1193 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus 8816480
Q07889 (SOS1) S1197 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus 8816480
Q08493-2 (PDE4C) S535 PhosphoSitePlus 11030732
Q08493 (PDE4C) S641 Signor 11030732
Q08499-5 (PDE4D) S413 PhosphoSitePlus 10828059
Q08499-4 (PDE4D) S490 PhosphoSitePlus 10828059
Q08499-2 (PDE4D) S579 PhosphoSitePlus   Signor 11030732, 16973330, 10828059, ...10022832
Q08499 (PDE4D) S715 Signor 16973330, 10828059, 10022832
Q09472 (EP300) T317 neXtProt   PhosphoSitePlus 17623675
Q09472 (EP300) T938 neXtProt   PhosphoSitePlus 17623675
Q09472 (EP300) S1038 RLIMS-P+ 24530506
Q09472 (EP300) T1960 neXtProt   PhosphoSitePlus 17623675
Q09472 (EP300) S2039 RLIMS-P+ 24530506
Q09472 (EP300) S2279 neXtProt   PhosphoSitePlus   Signor 17623675
Q09472 (EP300) S2315 neXtProt   PhosphoSitePlus   Signor 17623675
Q09472 (EP300) S2366 neXtProt   PhosphoSitePlus   Signor 17623675
Q09666 (AHNAK) S216 neXtProt 22028470
Q09666 (AHNAK) T694 neXtProt 22028470
Q09666 (AHNAK) S5099 neXtProt 22028470
Q09666 (AHNAK) S5110 neXtProt 22028470
Q09666 (AHNAK) T5794 neXtProt 22028470
Q12772 (SREBF2) S432 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 14988395
Q12772 (SREBF2) S455 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 14988395
Q12778 (FOXO1) S246 neXtProt 17113751
Q12778 (FOXO1) S413 neXtProt 17113751
Q12778 (FOXO1) S418 neXtProt 17113751
Q12778 (FOXO1) S429 neXtProt 17113751
Q12778 (FOXO1) S470 neXtProt 17113751
Q12778 (FOXO1) T478 neXtProt 17113751
Q12778 (FOXO1) T560 neXtProt 17113751
Q12800 (TFCP2) S291 Signor 19237534
Q12800 (TFCP2) S309 Signor 19237534
Q13153 (PAK1) T212 phospho.ELM 15542607
Q13164 (MAPK7) T733 neXtProt   PhosphoSitePlus 25689862
Q13285 (NR5A1) S203 HPRD   PhosphoSitePlus 19995909, 10230405
Q13322-3 (GRB10) S92 HPRD 15952796
Q13322 (GRB10) S150 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 15952796
Q13322-3 (GRB10) S360 HPRD 18669648, 15952796
Q13322-2 (GRB10) S372 HPRD 18669648, 15952796
Q13322 (GRB10) S418 HPRD   neXtProt 18669648, 15952796, 20068231
Q13322-2 (GRB10) S430 HPRD 18669648, 15952796, 20068231
Q13322 (GRB10) S476 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 18669648, 15952796, 20068231
Q13362 (PPP2R5C) S337 Signor 16456541
Q13409 (DYNC1I2) S87 neXtProt 19767751, 22028470
Q13459 (MYO9B) T1346 neXtProt 22028470
Q13480-1 (GAB1) T312 HPRD   neXtProt 15379552
Q13480-2 (GAB1) S381 HPRD   neXtProt 15379552
Q13480 (GAB1) S454 HPRD   neXtProt 15379552
Q13480 (GAB1) T476 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus 15379552
Q13480-1 (GAB1) S551 HPRD 15379552
Q13480-1 (GAB1) S567 HPRD 15379552
Q13480-2 (GAB1) S581 HPRD 15379552
Q13480 (GAB1) S582 neXtProt 15379552
Q13480 (GAB1) S597 HPRD   neXtProt 15379552
Q13485 (SMAD4) T277 HPRD   Signor 12801888
Q13541 (EIF4EBP1) T37 HPRD   neXtProt   PhosphoSitePlus   Signor 11777913, 19413330, 10942774, ...19664995, 19651622, 18669648, 11691836, 20068231
Q13541 (EIF4EBP1) T45 Signor 11777913
Q13541 (EIF4EBP1) T46 HPRD   neXtProt   PhosphoSitePlus   Signor 11777913, 19413330, 10942774, ...19664995, 19651622, 18669648, 11691836, 20068231
Q13541 (EIF4EBP1) S65 HPRD   neXtProt   PhosphoSitePlus   Signor 11777913, 17287340, 18767875, ...10942774, 19664995, 11691836, 19651622, 18669648, 8083223, 20068231
Q13541 (EIF4EBP1) T70 HPRD   neXtProt   PhosphoSitePlus   Signor 17287340, 10942774, 19664995, ...19651622, 18669648, 12747827, 11691836, 20068231
Q13541 (EIF4EBP1) S83 HPRD   Signor 10779345, 18669648, 11691836, ...9092573, 9405468
Q13562 (NEUROD1) S162 neXtProt 12810726
Q13562 (NEUROD1) S259 neXtProt 12810726
Q13562 (NEUROD1) S266 neXtProt 12810726
Q13562 (NEUROD1) S274 neXtProt 12810726
Q13586 (STIM1) S575 PhosphoSitePlus   RLIMS-P+   Signor 25447552, 22298426, 23687376, ...25562429
Q13586 (STIM1) S608 PhosphoSitePlus   RLIMS-P+ 25447552, 23687376, 25562429
Q13586 (STIM1) S621 PhosphoSitePlus   RLIMS-P+ 23687376, 25447552, 25562429
Q13614 (MTMR2) S58 PhosphoSitePlus 23378027
Q13625 (TP53BP2) T586 neXtProt 22028470
Q13625 (TP53BP2) S827 PhosphoSitePlus 24312625
Q14005 (IL16) S845 Signor 14768064
Q14151 (SAFB2) S343 neXtProt 22028470
Q14157-1 (UBAP2L) T844 neXtProt 22028470
Q14185 (DOCK1) T1772 neXtProt 22028470
Q14247 (CTTN) S405 neXtProt   PhosphoSitePlus   Signor 20444238, 21079800, 10537323
Q14247 (CTTN) S418 neXtProt   PhosphoSitePlus   Signor 20444238, 21079800, 10537323
Q14643 (ITPR1) S436 neXtProt 16925983
Q14643 (ITPR1) S1774 neXtProt 16925983
Q14654 (KCNJ11) T341 neXtProt 18280666
Q14654 (KCNJ11) S385 neXtProt 18280666
Q14674 (ESPL1) S1126 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 11747808
Q14686 (NCOA6) S884 neXtProt   PhosphoSitePlus 11773444, 11301320
Q14790 (CASP8) S387 PhosphoSitePlus   Signor 24342355
Q14934 (NFATC4) S676 phospho.ELM   PhosphoSitePlus   Signor 15657420
Q15366 (PCBP2) S173 RLIMS-P+   Signor 17475908
Q15366 (PCBP2) S189 RLIMS-P+   Signor 17475908
Q15366 (PCBP2) T213 RLIMS-P+   Signor 17475908
Q15366 (PCBP2) S272 RLIMS-P+   Signor 17475908
Q15398 (DLGAP5) T329 neXtProt 22028470
Q15418-1 (RPS6KA1) T359 HPRD 18691976, 18212344, 9430688, ...19651622, 18669648, 20068231
Q15418-1 (RPS6KA1) S363 HPRD 18691976, 12618428, 9430688, ...19651622, 18669648, 20068231
Q15418-2 (RPS6KA1) T368 HPRD 18691976, 18212344, 9430688, ...19651622, 18669648, 20068231
Q15418-2 (RPS6KA1) S372 HPRD 18691976, 12618428, 9430688, ...19651622, 18669648, 20068231
Q15418 (RPS6KA1) T573 PhosphoSitePlus   Signor 25730857, 9687510
Q15596 (NCOA2) S736 neXtProt   PhosphoSitePlus 11301320
Q15648 (MED1) T1032 PhosphoSitePlus   Signor 16314496
Q15648 (MED1) T1457 phospho.ELM   PhosphoSitePlus   Signor 12356758, 16314496
Q15672 (TWIST1) S6 neXtProt 21502402
Q15672 (TWIST1) S68 PhosphoSitePlus   Signor 21502402
Q15700 (DLG2) S323 PhosphoSitePlus 22618309
Q15746 (MYLK) S1779 PhosphoSitePlus 11964068
Q15788-3 (NCOA1) S395 HPRD   phospho.ELM   PhosphoSitePlus   Signor 10660621, 20068231
Q15788 (NCOA1) T1179 HPRD   phospho.ELM   PhosphoSitePlus   Signor 10660621
Q15788-1 (NCOA1) S1185 HPRD   phospho.ELM   PhosphoSitePlus   Signor 10660621
Q15796 (SMAD2) T220 HPRD   PhosphoSitePlus   Signor 12193595, 10197981
Q15796 (SMAD2) S245 HPRD   PhosphoSitePlus   Signor 12193595, 10197981
Q15796 (SMAD2) S250 HPRD   PhosphoSitePlus   Signor 12193595, 10197981
Q15796 (SMAD2) S255 PhosphoSitePlus   Signor 12193595, 10197981
Q15797 (SMAD1) S187 phospho.ELM   PhosphoSitePlus   Signor 9335504, 19914161, 19914168
Q15797 (SMAD1) S195 HPRD   phospho.ELM   PhosphoSitePlus   Signor 9335504, 19914161, 19914168
Q15797 (SMAD1) S206 HPRD   phospho.ELM   PhosphoSitePlus   Signor 9335504, 17289590, 19914161, ...19914168
Q15797 (SMAD1) S214 HPRD   phospho.ELM   PhosphoSitePlus   Signor 9335504, 19914161, 19914168
Q15831 (STK11) S428 Signor 25846811
Q16526 (CRY1) S247 neXtProt 15298678
Q16665 (HIF1A) S641 neXtProt   PhosphoSitePlus   Signor 18519666, 18687685, 16954218
Q16665 (HIF1A) S643 neXtProt   PhosphoSitePlus   Signor 18519666, 18687685, 16954218
Q16690 (DUSP5) T321 PhosphoSitePlus 19666109
Q16690 (DUSP5) S346 PhosphoSitePlus 19666109
Q16690 (DUSP5) S376 PhosphoSitePlus 19666109
Q16828 (DUSP6) S159 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 15632084
Q16828 (DUSP6) S197 HPRD   neXtProt   PhosphoSitePlus   Signor 15632084
Q49AN0 (CRY2) S266 neXtProt 15298678
Q53EZ4 (CEP55) S425 HPRD   neXtProt   PhosphoSitePlus   Signor 19413330, 18691976, 16964243, ...18669648, 16198290, 19415658, 20068231
Q53EZ4-1 (CEP55) S428 HPRD   neXtProt   PhosphoSitePlus   Signor 19413330, 18691976, 18767875, ...19664994, 19691289, 18452278, 18669648, 16198290, 19415658, 20068231
Q5SW79 (CEP170) T565 neXtProt 22028470
Q5VZ89 (DENND4C) S989 neXtProt 22028470
Q6P0Q8 (MAST2) S1337 neXtProt 22028470
Q6P996 (PDXDC1) T691 neXtProt 22028470
Q6PKG0 (LARP1) T303 neXtProt 22028470
Q6PKG0 (LARP1) S774 neXtProt 22028470
Q6Y7W6 (GIGYF2) S30 neXtProt 22028470
Q6ZS17 (RIPOR1) S351 neXtProt 22028470
Q70E73 (RAPH1) S610 neXtProt 22028470
Q7L5N1 (COPS6) S148 PhosphoSitePlus 26267535
Q7LDG7 (RASGRP2) S394 RLIMS-P+ 27107697
Q7Z5J4 (RAI1) T1068 neXtProt 22028470
Q86UC2 (RSPH3) T243 Signor 19684019
Q86UC2 (RSPH3) T286 neXtProt   Signor 19684019
Q86UR1 (NOXA1) S239 neXtProt 20110267
Q86UR1 (NOXA1) S282 neXtProt   PhosphoSitePlus   Signor 20230789, 20110267
Q86UU1 (PHLDB1) S443 neXtProt 22028470
Q86UU1 (PHLDB1) S461 neXtProt 22028470
Q86WB0 (ZC3HC1) S354 neXtProt 22955283
Q86WB0 (ZC3HC1) S359 neXtProt 22955283
Q8IUW5 (RELL1) T261 neXtProt 22028470
Q8IUX7 (AEBP1) T621 neXtProt 15654748
Q8IUX7 (AEBP1) T1012 neXtProt 15654748
Q8IVF2 (AHNAK2) T510 neXtProt 22028470
Q8IVT5-4 (KSR1) T137 HPRD 18669648, 9858547
Q8IVT5-4 (KSR1) T151 HPRD 9858547
Q8IVT5-4 (KSR1) S320 HPRD 9858547
Q8IW41 (MAPKAPK5) T182 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 9628874, 21666810
Q8IX03 (WWC1) S542 PhosphoSitePlus 24269383
Q8IX03 (WWC1) S548 PhosphoSitePlus   Signor 24269383
Q8IYB8 (SUPV3L1) S725 neXtProt 22028470
Q8IZP0 (ABI1) S183 neXtProt   PhosphoSitePlus   Signor 21419341
Q8IZP0 (ABI1) S216 neXtProt   PhosphoSitePlus 21419341
Q8IZP0 (ABI1) S222 Signor 21419341
Q8IZP0 (ABI1) S225 neXtProt   PhosphoSitePlus   Signor 21419341
Q8IZP0 (ABI1) T265 neXtProt   PhosphoSitePlus 21419341
Q8IZP0 (ABI1) S267 neXtProt   PhosphoSitePlus 21419341
Q8IZP0 (ABI1) S392 neXtProt   PhosphoSitePlus 21419341
Q8IZP0 (ABI1) T394 neXtProt   PhosphoSitePlus 21419341
Q8IZP0 (ABI1) S410 neXtProt   PhosphoSitePlus 21419341
Q8IZQ8 (MYOCD) S815 neXtProt 19776005
Q8IZQ8 (MYOCD) S862 neXtProt 19776005
Q8IZQ8 (MYOCD) S869 neXtProt 19776005
Q8IZQ8 (MYOCD) T896 neXtProt 19776005
Q8N122 (RPTOR) S8 PhosphoSitePlus   Signor 21071439
Q8N122 (RPTOR) S696 PhosphoSitePlus   Signor 21071439, 21325048
Q8N122 (RPTOR) S863 PhosphoSitePlus   Signor 21071439
Q8N1G1 (REXO1) T269 neXtProt 22028470
Q8N9N5 (BANP) T337 PhosphoSitePlus 26080397
Q8N9N5 (BANP) T352 PhosphoSitePlus 26080397
Q8NEL9 (DDHD1) S727 neXtProt 11328814
Q8NHW3 (MAFA) S14 HPRD   neXtProt   PhosphoSitePlus   Signor 11416124
Q8NHW3 (MAFA) S65 HPRD   neXtProt   PhosphoSitePlus   Signor 11416124
Q8TDM6 (DLG5) T1279 neXtProt 22028470
Q8TER0 (SNED1) T1239 neXtProt 22028470
Q8WX93 (PALLD) S688 PhosphoSitePlus 22216253
Q8WX93 (PALLD) S808 PhosphoSitePlus 22216253
Q92731 (ESR2) S105 neXtProt 10230404
Q92793 (CREBBP) S93 PhosphoSitePlus 21751375
Q92908 (GATA6) S266 neXtProt   PhosphoSitePlus 18454176
Q92934 (BAD) S75 PhosphoSitePlus 25681438
Q92974 (ARHGEF2) T679 PhosphoSitePlus   Signor 19261619, 18211802
Q93062 (RBPMS) T118 neXtProt 22028470
Q969H0 (FBXW7) T205 PhosphoSitePlus 25753158
Q969V6 (MRTFA) S454 PhosphoSitePlus   Signor 18694962, 22139079
Q96BY7 (ATG2B) T398 neXtProt 22028470
Q96EP5 (DAZAP1) T269 neXtProt   PhosphoSitePlus   Signor 16848763
Q96EP5 (DAZAP1) T315 neXtProt   PhosphoSitePlus   Signor 16848763
Q96FF9 (CDCA5) S79 neXtProt   PhosphoSitePlus 20551060
Q96FF9 (CDCA5) S209 neXtProt   PhosphoSitePlus 20551060
Q96I25 (RBM17) T71 PhosphoSitePlus 22615491
Q96I25 (RBM17) S222 PhosphoSitePlus 22615491
Q96LC9 (BMF) S74 neXtProt   PhosphoSitePlus   Signor 22258404
Q96LC9 (BMF) S77 neXtProt   PhosphoSitePlus   Signor 22258404
Q96LL9 (DNAJC30) S137 neXtProt 22028470
Q96PE2 (ARHGEF17) T702 neXtProt 22028470
Q96PH1-4 (NOX5) S498 PhosphoSitePlus 21297032
Q96PH1 (NOX5) S544 Signor 21297032
Q96Q27 (ASB2) S323 PhosphoSitePlus 24044920
Q96RK0 (CIC) S1389 PhosphoSitePlus 21087211
Q96RK0 (CIC) S1409 PhosphoSitePlus   Signor 21087211
Q96RS0 (TGS1) S298 PhosphoSitePlus 24358311
Q96SB3 (PPP1R9B) S15 HPRD   Signor 15728359
Q9BQG0 (MYBBP1A) S1267 neXtProt 22028470
Q9BQQ3 (GORASP1) S274 neXtProt 15834132
Q9BUB5 (MKNK1) T255 PhosphoSitePlus 17130135
Q9BWW4 (SSBP3) T360 neXtProt 22028470
Q9BY84 (DUSP16) S446 HPRD   phospho.ELM   PhosphoSitePlus 12794087
Q9BZI1 (IRX2) S46 neXtProt 15133517
Q9BZI1 (IRX2) S64 neXtProt 15133517
Q9C0C2 (TNKS1BP1) T131 neXtProt 22028470
Q9C0C2 (TNKS1BP1) T1032 neXtProt 22028470
Q9C0D5 (TANC1) S1564 neXtProt 22028470
Q9GZM8 (NDEL1) T219 PhosphoSitePlus 12556484
Q9GZM8 (NDEL1) T245 PhosphoSitePlus 12556484
Q9H0D6 (XRN2) T439 neXtProt 22028470
Q9H8Y8 (GORASP2) T222 neXtProt   PhosphoSitePlus 11408587
Q9H8Y8 (GORASP2) T225 HPRD   neXtProt   PhosphoSitePlus   Signor 19413330, 17287340, 18767875, ...19651622, 11408587, 20068231
Q9H9S0 (NANOG) S52 neXtProt 24793005, 24678451
Q9H9S0 (NANOG) S71 neXtProt 24793005
Q9H9S0 (NANOG) T78 neXtProt 24793005
Q9HAV4 (XPO5) T345 Signor 27846390
Q9HAV4 (XPO5) S416 Signor 27846390
Q9HAV4 (XPO5) S497 Signor 27846390
Q9HBH9 (MKNK2) S43 neXtProt 11154262
Q9HBH9 (MKNK2) S74 neXtProt 11154262
Q9HBH9 (MKNK2) S220 neXtProt 11154262
Q9HBH9 (MKNK2) T379 neXtProt 11154262
Q9HBH9 (MKNK2) S440 neXtProt 11154262
Q9HBH9 (MKNK2) S452 neXtProt 11154262
Q9NQ66 (PLCB1) S982 PhosphoSitePlus 11287604
Q9NQC3 (RTN4) T172 neXtProt 22028470
Q9NRA0 (SPHK2) S387 neXtProt   PhosphoSitePlus   Signor 17311928
Q9NRA0 (SPHK2) T614 neXtProt   PhosphoSitePlus   Signor 17311928
Q9NRA8 (EIF4ENIF1) S115 neXtProt 22028470
Q9NRF2 (SH2B1) S96 PhosphoSitePlus 10473609
Q9NSI2 (FAM207A) S39 neXtProt 22028470
Q9NUY8 (TBC1D23) T514 neXtProt 22028470
Q9NVD7 (PARVA) S4 Signor 22955285
Q9NVD7 (PARVA) S8 Signor 22955285
Q9NXR1 (NDE1) T215 HPRD   Signor 12556484, 18669648, 20068231
Q9NXR1 (NDE1) S239 HPRD   Signor 12556484, 18669648, 20068231
Q9NYA1 (SPHK1) S225 PhosphoSitePlus   Signor 16522638, 14532121
Q9NYZ3 (GTSE1) S461 neXtProt 22028470
Q9NZ72 (STMN3) S68 PhosphoSitePlus 22577147
Q9NZV8 (KCND2) T602 neXtProt 11080179
Q9NZV8 (KCND2) T607 neXtProt 11080179
Q9NZV8 (KCND2) S616 neXtProt 11080179
Q9P0K7 (RAI14) T249 neXtProt 22028470
Q9UBN7 (HDAC6) T1031 PhosphoSitePlus 24089523
Q9UHB6 (LIMA1) S362 RLIMS-P+   Signor 23188829
Q9UHB6 (LIMA1) S604 RLIMS-P+   Signor 23188829
Q9UKX7 (NUP50) S221 PhosphoSitePlus   Signor 19767751
Q9UKX7 (NUP50) S315 PhosphoSitePlus   Signor 19767751
Q9ULC4 (MCTS1) T81 PhosphoSitePlus 17016429
Q9ULW0 (TPX2) T369 neXtProt 22028470
Q9UNA1 (ARHGAP26) S685 neXtProt 9525907
Q9UPT5 (EXOC7) S250 neXtProt   PhosphoSitePlus   Signor 22595671
Q9UQC2 (GAB2) S623 HPRD   neXtProt   PhosphoSitePlus   Signor 15356145
Q9Y463 (DYRK1B) S421 PhosphoSitePlus 26346493
Q9Y4F5 (CEP170B) S969 neXtProt 22028470
Q9Y4H2 (IRS2) T657 neXtProt 22028470
Q9Y4K1 (CRYBG1) S675 neXtProt 22028470
Q9Y698 (CACNG2) T321 neXtProt 19968761
Q9Y6G9 (DYNC1LI1) S516 neXtProt 19767751, 22028470
Q9Y6W5 (WASF2) S296 neXtProt   PhosphoSitePlus 21419341
Q9Y6W5 (WASF2) S308 neXtProt   PhosphoSitePlus 21419341


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048314 (hMAPK1/InitMet-/Phos:1) pT185,pY187 PRO
PR:000026341 (hMAPK1/iso:1/Phos:1) pT185,pY187 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O96017 (CHEK2) T68 P28482 (MAPK1) unknown eFIP 21772273
Phosphorylation P28482 (MAPK1) S202 P35813 (PPM1A) unknown eFIP 23560844
Phosphorylation P51636 (CAV2) Y19 P28482 (MAPK1) unknown eFIP 19778377
Phosphorylation Q02750 (MAP2K1) S298 P28482 (MAPK1) increased_association eFIP 17928366
Phosphorylation Q02750 (MAP2K1) S298 P28482 (MAPK1) increased_association eFIP 14993270
Phosphorylation Q15121 (PEA15) S104 P28482 (MAPK1) increased_association eFIP 15916534
Phosphorylation Q69559 (U24) T6 P28482 (MAPK1) unknown eFIP 18616943


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000026341 (hMAPK1/iso:1/Phos:1) Interaction PRO 16291755


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S142 L142 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T181 K181 Biomuta DOID:3571 / liver cancer [ icgc ]
T185 K185 Biomuta DOID:3571 / liver cancer [ icgc ]
G204 S204 Biomuta DOID:3070 / malignant glioma [ tcga ]
G204 C204 Biomuta DOID:0070003 / blastoma [ cosmic ]
T206 I206 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K259 R259 Biomuta DOID:363 / uterine cancer [ tcga ]
Y263 C263 Biomuta DOID:3070 / malignant glioma [ cosmic, icgc, tcga ]
K285 T285 Biomuta DOID:363 / uterine cancer [ tcga ]
Y316 C316 Biomuta DOID:5041 / esophageal cancer [ tcga ]