iPTMnet Report for P28472 (GABRB3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P28472 / GBRB3_HUMAN
Protein Name Gamma-aminobutyric acid receptor subunit beta-3 precursor
Gene Name Name: GABRB3
Organism Homo sapiens (Human)

PRO ID PR:P28472
DAG View
PRO Name gamma-aminobutyric acid receptor subunit beta-3 (human)
Definition A gamma-aminobutyric acid receptor subunit beta-3 that is encoded in the genome of human.
Short Label hGABRB3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P28472 (GABRB3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N33 N-Glycosylation GlyGen   UniProt 24909990
K43 Ubiquitination PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
N105 N-Glycosylation GlyGen   UniProt 24909990
K127 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
N174 N-Glycosylation GlyGen   UniProt 24909990
K198 Ubiquitination PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S35 Phosphorylation PhosphoSitePlus
T40 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T40 M40 Biomuta DOID:9256 / colorectal cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
N105 T105 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K127 N127 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K128 T128 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K128 M128 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ]
K128 N128 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K198 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S432 Y432 Biomuta DOID:1324 / lung cancer [ cosmic ]
S433 L433 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]