iPTMnet Report for P28370 (SMARCA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P28370 / SMCA1_HUMAN
Protein Name Probable global transcription activator SNF2L1
Gene Name Name: SMARCA1
Synonyms:SNF2L,SNF2L1;
Organism Homo sapiens (Human)

PRO ID PR:P28370
DAG View
PRO Name probable global transcription activator SNF2L1 (human)
Definition A probable global transcription activator SNF2L1 that is encoded in the genome of human.
Short Label hSMARCA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P28370 (SMARCA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y83 Phosphorylation PhosphoSitePlus
T102 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus   UniProt 21406692
T118 Phosphorylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus   UniProt 21406692
S137 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
Y144 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
S161 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
T374 Phosphorylation PhosphoSitePlus
Y416 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
K443 Acetylation PhosphoSitePlus
K443 Ubiquitination PhosphoSitePlus
K639 Ubiquitination PhosphoSitePlus
S644 Phosphorylation PhosphoSitePlus
S657 Phosphorylation PhosphoSitePlus
K659 Ubiquitination PhosphoSitePlus
K662 Ubiquitination PhosphoSitePlus
K680 Ubiquitination PhosphoSitePlus
T685 Phosphorylation PhosphoSitePlus
S713 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S714 Phosphorylation PhosphoSitePlus
S725 Phosphorylation PhosphoSitePlus
K754 Sumoylation PhosphoSitePlus
K754 Ubiquitination PhosphoSitePlus
Y757 Phosphorylation PhosphoSitePlus
Y762 Phosphorylation PhosphoSitePlus
S770 Phosphorylation PhosphoSitePlus
K814 Ubiquitination PhosphoSitePlus
K851 Acetylation PhosphoSitePlus
K851 Ubiquitination PhosphoSitePlus
K870 Ubiquitination PhosphoSitePlus
K874 Ubiquitination PhosphoSitePlus
K944 Sumoylation PhosphoSitePlus
K944 Ubiquitination PhosphoSitePlus
Y954 Phosphorylation UniProt 12112843
K960 Acetylation PhosphoSitePlus
K960 Ubiquitination PhosphoSitePlus
Y962 Phosphorylation PhosphoSitePlus
Y985 Phosphorylation PhosphoSitePlus
K1038 Acetylation PhosphoSitePlus
K1039 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S112 Phosphorylation HPRD 17081983
S116 Phosphorylation HPRD 19413330, 19651622
T118 Phosphorylation HPRD 19413330, 19651622
S119 Phosphorylation HPRD 19413330, 19651622, 19664995
Y416 Phosphorylation HPRD 20068231
S713 Phosphorylation HPRD 18669648
S725 Phosphorylation HPRD 18691976
S770 Phosphorylation HPRD 19691289
S1021 Phosphorylation HPRD 20068231, 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S116 Y116 Biomuta DOID:363 / uterine cancer [ icgc ]
T118 A118 Biomuta DOID:1319 / brain cancer [ cosmic ]
S159 F159 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K443 R443 Biomuta DOID:1324 / lung cancer [ cosmic ]
K639 Q639 Biomuta DOID:363 / uterine cancer [ icgc ]
S657 T657 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K680 * Biomuta DOID:10534 / stomach cancer [ cosmic, tcga ]
S725 R725 Biomuta DOID:363 / uterine cancer [ icgc ]
S725 I725 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
Y762 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K851 N851 Biomuta DOID:363 / uterine cancer [ icgc ]
K851 I851 Biomuta DOID:363 / uterine cancer [ icgc ]
Y985 C985 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1039 N1039 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]