iPTMnet Report for P28331 (NDUFS1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P28331 / NDUS1_HUMAN
Protein Name NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial precursor
Gene Name Name: NDUFS1
Organism Homo sapiens (Human)

PRO ID PR:P28331
DAG View
PRO Name NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (human)
Definition An NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial that is encoded in the genome of human.
Short Label hNDUFS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P28331 (NDUFS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation PhosphoSitePlus
K15 Ubiquitination PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
K84 Acetylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K157 Methylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
T239 Phosphorylation PhosphoSitePlus
S259 O-Glycosylation GlyGen 23301498, 28510447, 33465208, ...34229054
S264 O-Glycosylation GlyGen 33465208
T265 O-Glycosylation GlyGen 33465208
K289 Acetylation PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K298 Methylation PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
K311 Acetylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
Y316 Phosphorylation PhosphoSitePlus
T317 Phosphorylation PhosphoSitePlus
S318 O-Glycosylation GlyGen 23301498, 28510447, 33465208, ...34229054
K420 Ubiquitination PhosphoSitePlus
S434 Phosphorylation PhosphoSitePlus
T439 Phosphorylation PhosphoSitePlus
Y440 Phosphorylation PhosphoSitePlus
T441 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
K467 Acetylation PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
K470 Ubiquitination PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
S479 Phosphorylation PhosphoSitePlus
K499 Acetylation PhosphoSitePlus
K499 Ubiquitination PhosphoSitePlus
T503 Phosphorylation PhosphoSitePlus
S504 Phosphorylation PhosphoSitePlus
T507 Phosphorylation PhosphoSitePlus
K531 Ubiquitination PhosphoSitePlus
K607 Ubiquitination PhosphoSitePlus
T611 Phosphorylation PhosphoSitePlus
K621 Ubiquitination PhosphoSitePlus
R624 Methylation PhosphoSitePlus
T697 Phosphorylation PhosphoSitePlus
K709 Ubiquitination PhosphoSitePlus
C710 S-Nitrosylation dbSNO 26338901
C727 S-Nitrosylation dbSNO 26338901
Site PTM Type PTM Enzyme Score Source PMID
S478 Phosphorylation HPRD 20068231
S479 Phosphorylation HPRD 20068231
T595 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K471 N471 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R624 T624 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
C727 W727 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]