iPTMnet Report for P28324 (ELK4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P28324 / ELK4_HUMAN
Protein Name ETS domain-containing protein Elk-4
Gene Name Name: ELK4
Synonyms:SAP1;
Organism Homo sapiens (Human)

PRO ID PR:P28324
DAG View
PRO Name ETS domain-containing protein Elk-4 (human)
Definition An ETS domain-containing protein Elk-4 that is encoded in the genome of human.
Short Label hELK4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P28324 (ELK4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S107 Phosphorylation PhosphoSitePlus
K125 Acetylation PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
K164 Sumoylation PhosphoSitePlus
K167 Sumoylation PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
K179 Acetylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus   UniProt 23186163
T185 Phosphorylation PhosphoSitePlus
T194 Phosphorylation P24941 (CDK2) PhosphoSitePlus 26028036
S215 Phosphorylation PhosphoSitePlus
S230 Phosphorylation PhosphoSitePlus
S235 O-Glycosylation GlyGen 30459171
S305 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
K320 Acetylation PhosphoSitePlus
T361 Phosphorylation P27361 (MAPK3) neXtProt 9020136
T366 Phosphorylation P27361 (MAPK3) neXtProt 9020136
S381 Phosphorylation P27361 (MAPK3) , Q16539 (MAPK14) neXtProt   PhosphoSitePlus 9130707, 9020136
S387 Phosphorylation P24941 (CDK2) , Q16539 (MAPK14) , P27361 (MAPK3) neXtProt   PhosphoSitePlus 26028036, 9130707, 9020136
S419 Phosphorylation PhosphoSitePlus
T420 Phosphorylation P27361 (MAPK3) neXtProt   PhosphoSitePlus 9020136
S425 Phosphorylation P27361 (MAPK3) neXtProt   PhosphoSitePlus 9020136
Site PTM Type PTM Enzyme Score Source PMID
S215 Phosphorylation HPRD 18452278
Site PTM Type PTM Enzyme Score Source PMID
S215 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K178 T178 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S180 F180 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S230 F230 Biomuta DOID:4159 / skin cancer [ cosmic ]
S235 A235 Biomuta DOID:4159 / skin cancer [ cosmic ]
T420 A420 Biomuta DOID:363 / uterine cancer [ icgc ]