iPTMnet Report for P28290 (ITPRID2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P28290 / ITPI2_HUMAN
Protein Name Protein ITPRID2
Gene Name Name: ITPRID2
Synonyms:CS1;
Organism Homo sapiens (Human)

PRO ID PR:P28290
DAG View
PRO Name protein ITPRID2 (human)
Definition A protein ITPRID2 that is encoded in the genome of human.
Short Label hITPRID2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P28290 (ITPRID2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K77 Ubiquitination PhosphoSitePlus
T87 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S92 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 19369195, 23186163, 26947549, ...18669648, 24275569, 19690332, 20068231
S97 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
T165 Phosphorylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus   UniProt 23186163
K212 Ubiquitination PhosphoSitePlus
Y234 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus   UniProt 20068231, 24275569
S272 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
T275 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
T280 Phosphorylation PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
T291 Phosphorylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
K301 Acetylation PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
K323 Acetylation PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
S330 Phosphorylation PhosphoSitePlus   UniProt 19369195, 23186163
S352 Phosphorylation PhosphoSitePlus
S354 Phosphorylation PhosphoSitePlus
T358 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
S376 Phosphorylation PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
S410 Phosphorylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
K416 Ubiquitination PhosphoSitePlus
S419 Phosphorylation phospho.ELM 18669648
S424 Phosphorylation PhosphoSitePlus
S425 Phosphorylation phospho.ELM 18669648
S427 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S432 Phosphorylation phospho.ELM 18669648
S437 Phosphorylation PhosphoSitePlus
S441 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T442 Phosphorylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus   UniProt 24275569
T501 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
S536 Phosphorylation PhosphoSitePlus
T555 Phosphorylation PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
K581 Ubiquitination PhosphoSitePlus
S591 Phosphorylation PhosphoSitePlus
S593 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S641 Phosphorylation PhosphoSitePlus
S644 Phosphorylation PhosphoSitePlus   UniProt 24275569
K648 Ubiquitination PhosphoSitePlus
S652 Phosphorylation PhosphoSitePlus
Y657 Phosphorylation PhosphoSitePlus
T659 Phosphorylation PhosphoSitePlus
K664 Ubiquitination PhosphoSitePlus
S665 Phosphorylation PhosphoSitePlus
S668 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T682 Phosphorylation PhosphoSitePlus
S687 Phosphorylation PhosphoSitePlus
K701 Methylation PhosphoSitePlus
K701 Ubiquitination PhosphoSitePlus
S704 Phosphorylation PhosphoSitePlus
S706 Phosphorylation PhosphoSitePlus
S713 Phosphorylation PhosphoSitePlus
Y725 Phosphorylation PhosphoSitePlus
Y732 Phosphorylation PhosphoSitePlus
S737 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18669648, ...24275569, 20068231
S739 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18220336, ...18669648, 24275569
T742 Phosphorylation PhosphoSitePlus
T743 Phosphorylation PhosphoSitePlus
S746 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...24275569
S752 Phosphorylation PhosphoSitePlus
S759 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
K762 Ubiquitination PhosphoSitePlus
T764 Phosphorylation PhosphoSitePlus
S767 Phosphorylation PhosphoSitePlus   UniProt 23186163
S770 Phosphorylation PhosphoSitePlus
T772 Phosphorylation PhosphoSitePlus
Y773 Phosphorylation PhosphoSitePlus
K774 Ubiquitination PhosphoSitePlus
Y775 Phosphorylation PhosphoSitePlus
T776 Phosphorylation PhosphoSitePlus
K785 Ubiquitination PhosphoSitePlus
S794 Phosphorylation PhosphoSitePlus
K797 Ubiquitination PhosphoSitePlus
S798 Phosphorylation PhosphoSitePlus
S803 Phosphorylation PhosphoSitePlus   UniProt 23186163
S805 Phosphorylation phospho.ELM 15302935
S806 Phosphorylation PhosphoSitePlus
K808 Sumoylation PhosphoSitePlus
K808 Ubiquitination PhosphoSitePlus
T828 Phosphorylation PhosphoSitePlus
S832 Phosphorylation PhosphoSitePlus
S840 Phosphorylation PhosphoSitePlus
T843 Phosphorylation PhosphoSitePlus
T864 Phosphorylation PhosphoSitePlus
S866 Phosphorylation PhosphoSitePlus
T867 Phosphorylation PhosphoSitePlus
S869 Phosphorylation PhosphoSitePlus
S883 Phosphorylation PhosphoSitePlus
T895 Phosphorylation PhosphoSitePlus
S902 Phosphorylation PhosphoSitePlus   UniProt 24275569
S923 Phosphorylation PhosphoSitePlus
Y930 Phosphorylation PhosphoSitePlus
S944 Phosphorylation PhosphoSitePlus
K947 Ubiquitination PhosphoSitePlus
S948 Phosphorylation PhosphoSitePlus
R972 Methylation PhosphoSitePlus
S1040 Phosphorylation PhosphoSitePlus
S1053 Phosphorylation PhosphoSitePlus
S1055 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S1060 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S1063 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 24275569
S1115 Phosphorylation PhosphoSitePlus
S1118 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1121 Phosphorylation PhosphoSitePlus
S1131 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T1132 Phosphorylation PhosphoSitePlus
S1134 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
T1140 Phosphorylation IEDB   PhosphoSitePlus 31848261, 27869121
S1152 Phosphorylation PhosphoSitePlus
T1156 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1158 Phosphorylation PhosphoSitePlus
S1161 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
T1163 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1165 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T1168 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S1174 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1175 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K1200 Ubiquitination PhosphoSitePlus
S1203 Phosphorylation PhosphoSitePlus
K1212 Ubiquitination PhosphoSitePlus
K1227 Ubiquitination PhosphoSitePlus
S1247 Phosphorylation PhosphoSitePlus
K1250 Ubiquitination PhosphoSitePlus
K1255 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T87 Phosphorylation HPRD 18669648
S92 Phosphorylation HPRD 18578522, 18767875, 19691289, ...18669648, 19415658, 20068231
S97 Phosphorylation HPRD 20068231
S111 Phosphorylation HPRD 20068231
S163 Phosphorylation HPRD 17081983
T165 Phosphorylation HPRD 17081983
S167 Phosphorylation HPRD 17081983
S168 Phosphorylation HPRD 17081983
S270 Phosphorylation HPRD 20166139, 19691289, 20068231
S273 Phosphorylation HPRD 20068231
S354 Phosphorylation HPRD 17081983
S410 Phosphorylation HPRD 19691289
S415 Phosphorylation HPRD 20068231
S419 Phosphorylation HPRD 18669648
S425 Phosphorylation HPRD 18669648
S427 Phosphorylation HPRD 18669648
S432 Phosphorylation HPRD 18669648
S441 Phosphorylation HPRD 18669648
S593 Phosphorylation HPRD 18578522, 18669648
S610 Phosphorylation HPRD 17081983
S668 Phosphorylation HPRD 18767875, 18669648, 19691289
S704 Phosphorylation HPRD 20068231
Y725 Phosphorylation HPRD 18452278
Y732 Phosphorylation HPRD 20068231
S737 Phosphorylation HPRD 17081983, 18767875, 19691289, ...19651622, 18669648, 20166139, 20068231, 18212344
S739 Phosphorylation HPRD 18578522, 18491316, 18212344, ...18767875, 20058876, 19691289, 19651622, 15302935, 18669648, 20166139, 19415658, 20068231
T743 Phosphorylation HPRD 17081983
S746 Phosphorylation HPRD 19651622, 18669648, 19415658, ...20068231, 19691289
S759 Phosphorylation HPRD 20068231
S767 Phosphorylation HPRD 19691289
S923 Phosphorylation HPRD 20068231
S1040 Phosphorylation HPRD 18767875, 20068231
S1044 Phosphorylation HPRD 20068231
S1045 Phosphorylation HPRD 20068231
S1055 Phosphorylation HPRD 17081983, 20068231
S1060 Phosphorylation HPRD 17081983, 20068231
S1063 Phosphorylation HPRD 17081983, 20068231
S1131 Phosphorylation HPRD 18669648, 20068231
T1132 Phosphorylation HPRD 19691289, 20068231
S1134 Phosphorylation HPRD 18669648, 20068231
T1140 Phosphorylation HPRD 19691289
S1152 Phosphorylation HPRD 19691289
T1156 Phosphorylation HPRD 19691289
T1158 Phosphorylation HPRD 19691289
S1161 Phosphorylation HPRD 19691289, 20068231
T1163 Phosphorylation HPRD 18669648, 17081983
S1165 Phosphorylation HPRD 18669648, 17081983
T1168 Phosphorylation HPRD 18669648, 17081983
S1174 Phosphorylation HPRD 18669648, 17081983
S1175 Phosphorylation HPRD 18669648, 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K77 N77 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T165 A165 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S167 L167 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S207 P207 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S209 F209 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T280 K280 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T280 S280 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S289 T289 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K311 T311 Biomuta DOID:363 / uterine cancer [ icgc ]
S330 L330 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S424 F424 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S536 R536 Biomuta DOID:3571 / liver cancer [ cosmic ]
S668 F668 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S704 N704 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y725 F725 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T743 I743 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T764 N764 Biomuta DOID:3571 / liver cancer [ cosmic ]
S767 C767 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y773 H773 Biomuta [ cosmic ]
S798 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S798 L798 Biomuta DOID:4159 / skin cancer [ cosmic ]
S806 F806 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S832 A832 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T843 P843 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S948 L948 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc, cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic, cosmic ] DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S948 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1121 C1121 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S1134 L1134 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
T1156 M1156 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T1156 A1156 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1165 F1165 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1168 S1168 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1203 L1203 Biomuta DOID:4159 / skin cancer [ cosmic ]