iPTMnet Report P28289 TMOD1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P28289 / TMOD1_HUMAN
Protein Name	Tropomodulin-1
Gene Name	Name: TMOD1 Synonyms:D9S57E,TMOD;
Organism	Homo sapiens (Human)

PRO ID	PR:P28289 DAG View
PRO Name	tropomodulin-1 (human)
Definition	A tropomodulin-1 that is encoded in the genome of human.
Short Label	hTMOD1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P28289 (TMOD1) as Substrate

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S2	Phosphorylation		score2	PhosphoSitePlus	19137675
	S2	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	19137675
	Y3	Phosphorylation		score1	PhosphoSitePlus
	Y10	Phosphorylation		score1	PhosphoSitePlus
	T23	Phosphorylation		score1	PhosphoSitePlus
	T54	Phosphorylation		score2	PhosphoSitePlus	19137675
	T54	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	19137675
	Y87	Phosphorylation		score1	PhosphoSitePlus
	Y225	Phosphorylation		score1	PhosphoSitePlus
	T234	Phosphorylation		score1	PhosphoSitePlus
	S236	Phosphorylation		score1	PhosphoSitePlus
	Y242	Phosphorylation		score1	PhosphoSitePlus
	Y278	Phosphorylation		score1	PhosphoSitePlus
	S329	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y87	Phosphorylation		score0	HPRD	17081983
	T88	Phosphorylation		score0	HPRD	17081983
	T234	Phosphorylation		score0	HPRD	18452278
	S236	Phosphorylation		score0	HPRD	18452278
	Y278	Phosphorylation		score0	HPRD	20068231

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
T54	N54	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
T88	K88	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
T234	A234	Biomuta		DOID:4159 / skin cancer [ cosmic ]
Y242	H242	Biomuta		DOID:1612 / breast cancer [ cosmic, icgc ]