iPTMnet Report for P28288 (ABCD3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P28288 / ABCD3_HUMAN
Protein Name ATP-binding cassette sub-family D member 3
Gene Name Name: ABCD3
Synonyms:PMP70,PXMP1;
Organism Homo sapiens (Human)

PRO ID PR:P28288
DAG View
PRO Name ATP-binding cassette sub-family D member 3 (human)
Definition An ATP-binding cassette sub-family D member 3 that is encoded in the genome of human.
Short Label hABCD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P28288 (ABCD3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Acetylation PhosphoSitePlus
K6 Ubiquitination PhosphoSitePlus
C24 S-Nitrosylation dbSNO 26338901
K38 Ubiquitination PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
S95 Phosphorylation PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus
Y163 Phosphorylation PhosphoSitePlus
Y173 Phosphorylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K260 Acetylation PhosphoSitePlus   UniProt 19608861
K260 Ubiquitination PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
Y357 Phosphorylation PhosphoSitePlus
Y358 Phosphorylation PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
T388 Phosphorylation PhosphoSitePlus
K399 Acetylation PhosphoSitePlus   UniProt 19608861
K399 Ubiquitination PhosphoSitePlus
K405 Acetylation PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
K416 Ubiquitination PhosphoSitePlus
T449 Phosphorylation PhosphoSitePlus
C472 S-Nitrosylation dbSNO 2212679, 22126794
K479 Ubiquitination PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
Y525 Phosphorylation PhosphoSitePlus
K533 Acetylation PhosphoSitePlus
K533 Ubiquitination PhosphoSitePlus
K535 Ubiquitination PhosphoSitePlus
K543 Ubiquitination PhosphoSitePlus
Y545 Phosphorylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
K576 Ubiquitination PhosphoSitePlus
K631 Acetylation PhosphoSitePlus
Y635 Phosphorylation PhosphoSitePlus
Y636 Phosphorylation PhosphoSitePlus
Y645 Phosphorylation PhosphoSitePlus
T654 Phosphorylation PhosphoSitePlus
S659 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T9 Phosphorylation HPRD 20068231
Y525 Phosphorylation HPRD 20068231


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:P40855-1 (hPEX19/iso:1) Interaction PR:P28288 (hABCD3) PRO 11883941
PR:P40855-2 (hPEX19/iso:2) Interaction PR:P28288 (hABCD3) PRO 11883941
PR:P40855-4 (hPEX19/iso:4) Interaction PR:P28288 (hABCD3) PRO 11883941


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S360 N360 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K416 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
T654 I654 Biomuta DOID:4159 / skin cancer [ cosmic ]
S659 F659 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]