iPTMnet Report for P28161 (GSTM2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P28161 / GSTM2_HUMAN
Protein Name Glutathione S-transferase Mu 2
Gene Name Name: GSTM2
Synonyms:GST4;
Organism Homo sapiens (Human)

PRO ID PR:P28161
DAG View
PRO Name glutathione S-transferase mu 2 (human)
Definition A glutathione S-transferase mu 2 that is encoded in the genome of human.
Short Label hGSTM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P28161 (GSTM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y23 Phosphorylation PhosphoSitePlus
T24 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K32 Acetylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
R43 Methylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
T67 Phosphorylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
T71 Phosphorylation PhosphoSitePlus
R78 Methylation PhosphoSitePlus
S139 O-Glycosylation GlyGen 30620550
K144 Acetylation PhosphoSitePlus
Y161 Phosphorylation IEDB 35494241
S186 Phosphorylation PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
K199 Acetylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K31 T31 Biomuta DOID:4159 / skin cancer [ cosmic ]
K31 N31 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
R43 K43 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
R78 W78 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, icgc ]
K199 N199 Biomuta DOID:3571 / liver cancer [ cosmic ]
S200 F200 Biomuta [ cosmic ]
S201 I201 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]