Protein Information

Cytoscape View


UniProt AC / UniProt ID P28074 / PSB5_HUMAN
Protein Name Proteasome subunit beta type-5 precursor
Gene Name Name: PSMB5
Synonyms:LMPX,MB1,X;
Organism Homo sapiens (Human)

PRO ID PR:P28074
DAG View
PRO Name proteasome subunit beta type-5 (human)
Definition A proteasome subunit beta type-5 that is encoded in the genome of human.
Short Label hPSMB5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P28074 (PSMB5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S87 Phosphorylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
Y99 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
Y147 Phosphorylation PhosphoSitePlus
Y149 Phosphorylation PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
Y171 Phosphorylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
Y212 Phosphorylation PhosphoSitePlus
Y220 Phosphorylation PhosphoSitePlus
Y228 Phosphorylation PhosphoSitePlus
Y236 Phosphorylation PhosphoSitePlus
S247 Phosphorylation PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus
K257 Acetylation PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
T262 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S139 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T158 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K92 N92 Biomuta DOID:363 / uterine cancer [ tcga ]
Y99 * Biomuta DOID:3571 / liver cancer [ icgc ]
K165 E165 Biomuta DOID:363 / uterine cancer [ tcga ]
Y212 C212 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:11934 / head and neck cancer [ tcga ] DOID:0070003 / blastoma [ cosmic ]
S247 C247 Biomuta DOID:11934 / head and neck cancer [ tcga ]
K257 T257 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S261 F261 Biomuta DOID:10283 / prostate cancer [ cosmic ]