Protein Information

Cytoscape View

UniProt AC / UniProt ID P28066 / PSA5_HUMAN
Protein Name Proteasome subunit alpha type-5
Gene Name Name: PSMA5
Organism Homo sapiens (Human)

PRO ID PR:P28066
DAG View
PRO Name proteasome subunit alpha type-5 (human)
Definition A proteasome subunit alpha type-5 that is encoded in the genome of human.
Short Label hPSMA5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P28066 (PSMA5) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
Y8 Phosphorylation PhosphoSitePlus
R10 Methylation PhosphoSitePlus
T14 Phosphorylation PhosphoSitePlus
S16 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243, ...20068231
R20 Methylation PhosphoSitePlus
Y26 Phosphorylation PhosphoSitePlus
T36 Phosphorylation PhosphoSitePlus
S43 Phosphorylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
T55 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18669648, 23907514
S56 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 17081983, 15302935, ...18669648, 20068231, 23907514
S62 Phosphorylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus   UniProt 23186163
K66 Ubiquitination PhosphoSitePlus
S79 Phosphorylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
K91 Acetylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K149 Sumoylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
Y185 Phosphorylation PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
K192 Sumoylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
K196 Sumoylation PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
S198 O-Glycosylation GlyGen 23301498, 18984734, 28510447, ...26374642
K203 Sumoylation PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
K209 Acetylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
T213 Phosphorylation RLIMS-P 23907514
T219 Phosphorylation RLIMS-P 23907514
K231 Sumoylation PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO
T14 Phosphorylation HPRD 20068231
S16 Phosphorylation HPRD 19413330, 18691976, 16964243, ...18767875, 19651622, 17322306, 18669648, 19415658, 20068231, 17924679
T55 Phosphorylation HPRD 19413330, 18691976, 17081983, ...19664995, 18669648, 20068231
S56 Phosphorylation HPRD 19413330, 18691976, 20058876, ...15302935, 19664995, 19651622, 18669648, 20068231
S63 Phosphorylation HPRD 20068231


PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036311 (hPSMA5/Ac:1) acM1 PRO

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S6 F6 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S16 F16 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T36 A36 Biomuta DOID:3277 / thymus cancer [ tcga ]
S43 L43 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K196 T196 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
T219 I219 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T219 K219 Biomuta DOID:3571 / liver cancer [ icgc ]