Protein Information

Cytoscape View


UniProt AC / UniProt ID P28062 / PSB8_HUMAN
Protein Name Proteasome subunit beta type-8 precursor
Gene Name Name: PSMB8
Synonyms:LMP7,PSMB5i,RING10,Y2;
Organism Homo sapiens (Human)

PRO ID PR:P28062
DAG View
PRO Name proteasome subunit beta type-8 (human)
Definition A proteasome subunit beta type-8 that is encoded in the genome of human.
Short Label hPSMB8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P28062 (PSMB8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R11 Methylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
Y112 Phosphorylation PhosphoSitePlus
Y126 Phosphorylation PhosphoSitePlus
K133 Acetylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
Y162 Phosphorylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
Y184 Phosphorylation PhosphoSitePlus
Y185 Phosphorylation PhosphoSitePlus
Y234 Phosphorylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
Y249 Phosphorylation PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
K258 Sumoylation PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T5 Phosphorylation HPRD   PhosphoSitePlus 18669648
Y180 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S28 * Biomuta DOID:5041 / esophageal cancer [ icgc ]
K153 N153 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
K258 N258 Biomuta DOID:5041 / esophageal cancer [ icgc ]