iPTMnet Report for P27824 (CANX)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P27824 / CALX_HUMAN
Protein Name Calnexin precursor
Gene Name Name: CANX
Organism Homo sapiens (Human)

PRO ID PR:P27824
DAG View
PRO Name calnexin (human)
Definition A calnexin that is encoded in the genome of human.
Short Label hCANX
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P27824 (CANX) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C8 Methylation IEDB 31844290
T49 O-Glycosylation GlyGen 30459171, 25813380
T50 O-Glycosylation GlyGen 30459171, 25813380
S54 O-Glycosylation GlyGen 25813380
T59 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 33214551, 30444036, ...32870666, 26853435, 34725712, 25813380, 34019948, 25128556, 35132862, 35083852, 31492838, 23584533, 34931806, 32119511, 28510447, 22661428, 29237092
K61 Ubiquitination PhosphoSitePlus
T66 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 33214551, 30444036, ...32870666, 26853435, 30459171, 34725712, 25813380, 34019948, 25128556, 35132862, 35083852, 31492838, 23584533, 34931806, 32119511, 28510447, 22661428
Y70 Phosphorylation PhosphoSitePlus
S74 O-Glycosylation GlyGen 22661428, 25128556
S74 Phosphorylation PhosphoSitePlus
R77 Methylation PhosphoSitePlus
T79 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S81 Phosphorylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
T93 Phosphorylation PhosphoSitePlus
K99 Acetylation PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K103 Acetylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
R125 Methylation PhosphoSitePlus
K127 Acetylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K134 Acetylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K137 Acetylation PhosphoSitePlus   UniProt 19608861
K137 Ubiquitination PhosphoSitePlus
Y150 Phosphorylation IEDB 35494241
K170 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
Y185 Phosphorylation PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
K199 Acetylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
T211 Phosphorylation PhosphoSitePlus
Y214 Phosphorylation PhosphoSitePlus
K217 Acetylation PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K227 Acetylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
T228 Phosphorylation PhosphoSitePlus
K233 Acetylation PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
R282 Methylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
Y379 Phosphorylation PhosphoSitePlus
K380 Ubiquitination PhosphoSitePlus
Y393 Phosphorylation PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
S431 Phosphorylation PhosphoSitePlus
K458 Acetylation PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
K459 Acetylation PhosphoSitePlus
K459 Ubiquitination PhosphoSitePlus
T509 Phosphorylation PhosphoSitePlus
S510 Phosphorylation PhosphoSitePlus
Y514 Phosphorylation PhosphoSitePlus
K516 Ubiquitination PhosphoSitePlus
K525 Ubiquitination PhosphoSitePlus
K537 Ubiquitination PhosphoSitePlus
K547 Ubiquitination PhosphoSitePlus
S554 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18691976, 21406692, 9642293, ...17081983, 18417615, 18318008, 18669648, 24275569, 23186163, 18088087, 20068231
T562 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16565220, ...18669648, 24275569
S564 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 9642293, 23186163, 17081983, ...18417615, 18669648, 24275569, 18088087, 19690332, 20068231
S583 Phosphorylation P27361 (MAPK3) , P06493 (CDK1) IEDB   phospho.ELM   PhosphoSitePlus   UniProt 9642293, 18691976, 21406692, ...16083285, 18088087, 17081983, 18234856, 35494241, 18669648, 19815548, 24275569, 23186163, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S392 Phosphorylation HPRD 20068231
S554 Phosphorylation HPRD 18691976, 18578522, 18088087, ...18212344, 18077418, 18452278, 19651622, 18669648, 18707149, 20166139, 9642293, 19415658, 20068231
T562 Phosphorylation HPRD 19651622, 18077418, 16565220, ...18669648, 18452278
S564 Phosphorylation HPRD 18578522, 18088087, 18212344, ...18767875, 18077418, 19007248, 18452278, 19651622, 18669648, 18707149, 20166139, 9642293, 19415658, 20068231
S583 Phosphorylation HPRD 19413330, 18691976, 18578522, ...18088087, 18212344, 18767875, 20058876, 19691289, 19664995, 17322306, 18510355, 18669648, 19651622, 18707149, 20166139, 18452278, 19415658, 20068231, 17924679


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P27824 (CANX) S564 Q86VP3 (PACS2) decreased_association eFIP 18417615