Protein Information

Cytoscape View


UniProt AC / UniProt ID P27487 / DPP4_HUMAN
Protein Name Dipeptidyl peptidase 4
Gene Name Name: DPP4
Synonyms:ADCP2,CD26;
Organism Homo sapiens (Human)

PRO ID PR:P27487
DAG View
PRO Name dipeptidyl peptidase 4 (human)
Definition A dipeptidyl peptidase IV that is encoded in the genome of human.
Short Label hDPP4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P27487 (DPP4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T44 Phosphorylation PhosphoSitePlus
T52 Phosphorylation PhosphoSitePlus
N85 N-Glycosylation GlyGen   UniProt 23835475, 12483204, 12646248, ...12906826, 20684603
N92 N-Glycosylation GlyGen   UniProt 23835475, 20684603, 19159218
N150 N-Glycosylation GlyGen   UniProt 12483204, 19159218, 24190977, ...12906826, 29391424, 23835475, 20684603
N151 N-Glycosylation GlyGen 24190977
N219 N-Glycosylation GlyGen   UniProt 23835475, 12483204, 12646248, ...20684603
N229 N-Glycosylation GlyGen   UniProt 23835475, 12483204, 12646248, ...12906826, 20684603
Y256 Phosphorylation PhosphoSitePlus
N263 N-Glycosylation GlyGen 29391424
N281 N-Glycosylation GlyGen   UniProt 23835475, 12483204, 12646248, ...12906826
N321 N-Glycosylation GlyGen   UniProt 23835475, 12483204, 12646248, ...24190977
Y439 Phosphorylation PhosphoSitePlus
T440 Phosphorylation PhosphoSitePlus
N520 N-Glycosylation GlyGen   UniProt 16335952, 12483204, 19159218, ...24190977, 29391424, 23835475, 20684603, 29741879
N679 N-Glycosylation GlyGen 24190977
Y683 Phosphorylation PhosphoSitePlus
N685 N-Glycosylation GlyGen   UniProt 16335952, 29741879, 29391424, ...19159218, 24190977


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T44 N44 Biomuta DOID:3571 / liver cancer [ icgc ]
N321 T321 Biomuta DOID:1324 / lung cancer [ tcga ]
N520 Y520 Biomuta DOID:5041 / esophageal cancer [ tcga ]