iPTMnet Report for P27144 (AK4)
Protein Information
| UniProt AC / UniProt ID | P27144 / KAD4_HUMAN |
| Protein Name | Adenylate kinase 4, mitochondrial |
| Gene Name | Name: AK4 Synonyms:AK3,AK3L1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P27144 |
| PRO Name | adenylate kinase 4, mitochondrial (human) |
| Definition | An adenylate kinase 4, mitochondrial that is encoded in the genome of human. |
| Short Label | hAK4 |
| Category | organism-gene |
DAG ViewP27144 (AK4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K4 | Acetylation | score1 | PhosphoSitePlus | |||
| S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T93 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C104 | Methylation | score1 | IEDB | 31844290 | ||
| K179 | Acetylation | score1 | PhosphoSitePlus | |||
| K179 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K186 | Acetylation | score1 | PhosphoSitePlus | |||
| R188 | Methylation | score1 | PhosphoSitePlus | |||
| Y205 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S219 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K220 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T93 | I93 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| C104 | Y104 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| R188 | Q188 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |
