Protein Information

Cytoscape View

UniProt AC / UniProt ID P27144 / KAD4_HUMAN
Protein Name Adenylate kinase 4, mitochondrial
Gene Name Name: AK4
Organism Homo sapiens (Human)

PRO ID PR:P27144
DAG View
PRO Name adenylate kinase 4, mitochondrial (human)
Definition An adenylate kinase 4, mitochondrial that is encoded in the genome of human.
Short Label hAK4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P27144 (AK4) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K4 Acetylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
T93 Phosphorylation PhosphoSitePlus
K179 Acetylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
K186 Acetylation PhosphoSitePlus
R188 Methylation PhosphoSitePlus
Y205 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T93 I93 Biomuta DOID:11934 / head and neck cancer [ tcga ]
R188 Q188 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]