Protein Information

Cytoscape View

UniProt AC / UniProt ID P27037 / AVR2A_HUMAN
Protein Name Activin receptor type-2A precursor
Gene Name Name: ACVR2A
Organism Homo sapiens (Human)

PRO ID PR:P27037
DAG View
PRO Name activin receptor type-2A (human)
Definition An activin receptor type-2A that is encoded in the genome of human.
Short Label hACVR2A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P27037 (ACVR2A) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S184 Phosphorylation PhosphoSitePlus
Y215 Phosphorylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
Y233 Phosphorylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
T486 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S184 Y184 Biomuta DOID:3571 / liver cancer [ icgc ]
Y215 C215 Biomuta DOID:4159 / skin cancer [ icgc ]
Y233 * Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K315 N315 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K351 E351 Biomuta DOID:363 / uterine cancer [ tcga ]
T486 A486 Biomuta DOID:363 / uterine cancer [ tcga ]