Protein Information

Cytoscape View


UniProt AC / UniProt ID P26715 / NKG2A_HUMAN
Protein Name NKG2-A/NKG2-B type II integral membrane protein
Gene Name Name: KLRC1
Synonyms:NKG2A;
Organism Homo sapiens (Human)

PRO ID PR:P26715
DAG View
PRO Name NKG2-A/NKG2-B type II integral membrane protein (human)
Definition An NKG2-A/NKG2-B type II integral membrane protein that is encoded in the genome of human.
Short Label hKLRC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P26715 (KLRC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y8 Phosphorylation PhosphoSitePlus   UniProt 12165520
Y40 Phosphorylation PhosphoSitePlus   UniProt 12165520
T89 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
T108 Phosphorylation PhosphoSitePlus
T110 Phosphorylation PhosphoSitePlus
S152 O-Glycosylation GlyGen 35289036
K195 Acetylation PhosphoSitePlus
K199 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y8 D8 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y40 H40 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S104 Y104 Biomuta DOID:363 / uterine cancer [ icgc ]
S104 F104 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S152 Y152 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K199 T199 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]