iPTMnet Report P26678 PLN

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P26678 / PPLA_HUMAN
Protein Name	Cardiac phospholamban
Gene Name	Name: PLN Synonyms:PLB;
Organism	Homo sapiens (Human)

PRO ID	PR:P26678 DAG View
PRO Name	cardiac phospholamban (human)
Definition	A cardiac phospholamban that is encoded in the genome of human.
Short Label	hPLN
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P26678 (PLN) as Substrate

P26678

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y6	Phosphorylation		score0	RLIMS-P	9601048
	S16	Phosphorylation	Q09013 (DMPK) , P17612 (PRKACA) , P31749 (AKT1)	score4	HPRD neXtProt phospho.ELM PRO PhosphoSitePlus RLIMS-P UniProt	11897526, 22155237, 9468536, ...12693956, 11852250, 10988285, 15528241, 29501609, 7711836, 32873725, 31325238, 33019581, 24813991, 16317512, 1530941, 22472319, 18081313, 21419777, 16564056, 28509982, 29057374, 12465028, 29431258, 25251363, 29593308, 22707725, 24550830, 27833092, 24511878, 11854448, 18838385, 3759968, 22463608, 29807087, 22959711, 35805951, 18508637, 15764655, 15598648, 26292938, 17548345, 18533723, 24895160, 36445386, 16226237, 12962492, 9601048
	T17	Phosphorylation	Q13557 (CAMK2D) , Q9UQM7 (CAMK2A) , Q13554 (CAMK2B)	score4	HPRD neXtProt phospho.ELM PhosphoSitePlus RLIMS-P UniProt	11897526, 16690701, 28509982, ...9468536, 35861968, 15528241, 18533723, 7711836, 24550830, 32873725, 16317512, 17234969, 16564056, 29057374, 29431258, 19608982, 3759968, 11852250, 19671701, 29807087, 22959711, 18508637, 21998325, 17913704, 18081313, 16226237, 26791827, 17766390

Proteoforms

	PRO ID (Short Label)	Sites	PTM Enzyme	Source	PMID
	PR:000048814 (hPLN/Phos:2)	pS16		PRO

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
T17	I17	Biomuta		DOID:4159 / skin cancer [ cosmic ]