iPTMnet Report for P26651 (ZFP36)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P26651 / TTP_HUMAN
Protein Name mRNA decay activator protein ZFP36
Gene Name Name: ZFP36
Synonyms:G0S24,NUP475;
Organism Homo sapiens (Human)

PRO ID PR:P26651
DAG View
PRO Name mRNA decay activator protein ZFP36 (human)
Definition An mRNA decay activator protein ZFP36 that is encoded in the genome of human.
Short Label hZFP36
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P26651 (ZFP36) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
S43 Phosphorylation PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
S52 Phosphorylation RLIMS-P 32039742
S60 Phosphorylation neXtProt   PRO   PhosphoSitePlus   RLIMS-P 26926077, 14688255
S60 Phosphorylation P49137 (MAPKAPK2) neXtProt 14688255
S66 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 14688255, 20221403, 16262601
S66 Phosphorylation P49137 (MAPKAPK2) neXtProt 14688255
R82 Methylation PhosphoSitePlus
S88 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16262601
S90 Phosphorylation PhosphoSitePlus
T92 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16262601
S93 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 20221403, 23186163
T95 Phosphorylation PhosphoSitePlus
T99 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
T111 Phosphorylation PhosphoSitePlus
S113 Phosphorylation neXtProt   PhosphoSitePlus 14688255
S113 Phosphorylation P49137 (MAPKAPK2) neXtProt 14688255
C118 Methylation IEDB 31844290
Y120 Phosphorylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
Y158 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
S169 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16262601
S184 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P 14688255, 20221403
S184 Phosphorylation P49137 (MAPKAPK2) neXtProt 14688255
S186 Phosphorylation neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   UniProt 20221403, 16262601, 28548957, ...18669648, 14688255, 23186163
S186 Phosphorylation P49137 (MAPKAPK2) neXtProt 14688255
S188 Phosphorylation PhosphoSitePlus
T196 Phosphorylation PhosphoSitePlus
S197 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16262601
S207 Phosphorylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus   RLIMS-P 25010646
S217 Phosphorylation PhosphoSitePlus
S218 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 16262601, 29246442, 25010646
S228 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 16262601, 25010646
S230 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
T238 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
T257 Phosphorylation neXtProt   PhosphoSitePlus 14688255
T257 Phosphorylation P49137 (MAPKAPK2) neXtProt 14688255
T271 Phosphorylation neXtProt   PhosphoSitePlus 14688255
T271 Phosphorylation P49137 (MAPKAPK2) neXtProt 14688255
S273 Phosphorylation neXtProt   PhosphoSitePlus 14688255
S273 Phosphorylation P49137 (MAPKAPK2) neXtProt 14688255
S276 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16262601
S279 Phosphorylation PhosphoSitePlus
Y284 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
S296 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16262601
S323 Phosphorylation neXtProt   PhosphoSitePlus   UniProt 14688255, 23186163
S323 Phosphorylation P49137 (MAPKAPK2) neXtProt 14688255
S325 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049725 (hZFP36/Phos:1) pS60,pS186 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S41 L41 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
T106 N106 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S279 P279 Biomuta DOID:9256 / colorectal cancer [ cosmic ]