iPTMnet Report for P26374 (CHML)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P26374 / RAE2_HUMAN
Protein Name Rab proteins geranylgeranyltransferase component A 2
Gene Name Name: CHML
Synonyms:REP2;
Organism Homo sapiens (Human)

PRO ID PR:P26374
DAG View
PRO Name Rab proteins geranylgeranyltransferase component A 2 (human)
Definition A Rab proteins geranylgeranyltransferase component A 2 that is encoded in the genome of human.
Short Label hCHML
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P26374 (CHML) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S161 Phosphorylation PhosphoSitePlus
S166 Phosphorylation PhosphoSitePlus
S192 O-Glycosylation GlyGen 23301498, 30379171
S235 Phosphorylation PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
T302 Phosphorylation PhosphoSitePlus
Y314 Phosphorylation PhosphoSitePlus
K419 Ubiquitination PhosphoSitePlus
K528 Ubiquitination PhosphoSitePlus
S641 Phosphorylation PhosphoSitePlus
S644 Phosphorylation PhosphoSitePlus
S649 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S166 * Biomuta DOID:363 / uterine cancer [ cosmic ]
S192 P192 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S235 L235 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S649 I649 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]