iPTMnet Report for P26367 (PAX6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P26367 / PAX6_HUMAN
Protein Name Paired box protein Pax-6
Gene Name Name: PAX6
Synonyms:AN2;
Organism Homo sapiens (Human)

PRO ID PR:P26367
DAG View
PRO Name paired box protein Pax-6 (human)
Definition A paired box protein Pax-6 that is encoded in the genome of human.
Short Label hPAX6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P26367 (PAX6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K55 Ubiquitination PhosphoSitePlus
S216 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T281 Phosphorylation neXtProt   Signor 16407227
T281 Phosphorylation Q9H2X6 (HIPK2) neXtProt   Signor 16407227
T304 Phosphorylation neXtProt   Signor 16407227
T304 Phosphorylation Q9H2X6 (HIPK2) neXtProt   Signor 16407227
T373 Phosphorylation neXtProt   PhosphoSitePlus   Signor 16407227
T373 Phosphorylation Q9H2X6 (HIPK2) neXtProt   Signor 16407227
Site PTM Type PTM Enzyme Score Source PMID
S216 Phosphorylation HPRD 18669648, 20068231
T281 Phosphorylation HPRD 16407227
T281 Phosphorylation Q9H2X6 (HIPK2) HPRD 16407227
T304 Phosphorylation HPRD 16407227
T304 Phosphorylation Q9H2X6 (HIPK2) HPRD 16407227
T373 Phosphorylation HPRD 16407227
T373 Phosphorylation Q9H2X6 (HIPK2) HPRD 16407227
Site PTM Type PTM Enzyme Score Source PMID
K53 Sumoylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
K89 Sumoylation PhosphoSitePlus
S230 Phosphorylation HPRD 18669648, 20068231
T295 Phosphorylation HPRD 16407227
T295 Phosphorylation Q9H2X6 (HIPK2) HPRD 16407227
T317 Phosphorylation HPRD 16407227
T317 Phosphorylation Q9H2X6 (HIPK2) HPRD 16407227
T387 Phosphorylation HPRD 16407227
T387 Phosphorylation Q9H2X6 (HIPK2) HPRD 16407227


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K89 T89 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T317 I317 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T373 S373 Biomuta DOID:1324 / lung cancer [ cosmic ]
T387 S387 Biomuta DOID:1324 / lung cancer [ cosmic ]