iPTMnet Report for P26232 (CTNNA2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P26232 / CTNA2_HUMAN
Protein Name Catenin alpha-2
Gene Name Name: CTNNA2
Synonyms:CAPR;
Organism Homo sapiens (Human)

PRO ID PR:P26232
DAG View
PRO Name catenin alpha-2 (human)
Definition A catenin alpha-2 that is encoded in the genome of human.
Short Label hCTNNA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P26232 (CTNNA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K15 Ubiquitination PhosphoSitePlus
T41 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
C115 Methylation IEDB 31844290
S151 Phosphorylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
C335 Methylation IEDB 31844290
K415 Ubiquitination PhosphoSitePlus
Y417 Phosphorylation PhosphoSitePlus
C524 Methylation IEDB 31844290
T535 Phosphorylation PhosphoSitePlus
R621 Methylation PhosphoSitePlus
S640 Phosphorylation PhosphoSitePlus   UniProt 21406692
S651 Phosphorylation PhosphoSitePlus
T653 Phosphorylation PhosphoSitePlus
S654 Phosphorylation PhosphoSitePlus
T657 Phosphorylation PhosphoSitePlus
S667 Phosphorylation PhosphoSitePlus
K696 Ubiquitination PhosphoSitePlus
T738 Phosphorylation PhosphoSitePlus
S739 Phosphorylation PhosphoSitePlus
S753 Phosphorylation PhosphoSitePlus
Y778 Phosphorylation PhosphoSitePlus
C786 Methylation IEDB 31844290
C792 Methylation IEDB 31844290
K889 Acetylation PhosphoSitePlus
K889 Ubiquitination PhosphoSitePlus
S939 Phosphorylation PhosphoSitePlus
S945 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation HPRD 20068231
S3 Phosphorylation HPRD 20068231
S6 Phosphorylation HPRD 20068231
S151 Phosphorylation HPRD 20068231
S262 Phosphorylation HPRD 15345747
S640 Phosphorylation HPRD 18510355, 15345747
T653 Phosphorylation HPRD 17081983
S654 Phosphorylation HPRD 17081983
S853 Phosphorylation HPRD 15345747


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 L3 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc, cosmic, cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
T41 K41 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S42 R42 Biomuta DOID:4159 / skin cancer [ cosmic ]
S151 F151 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S262 L262 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S302 P302 Biomuta DOID:363 / uterine cancer [ icgc ]
S302 F302 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S321 T321 Biomuta DOID:263 / kidney cancer [ cosmic ]
S321 C321 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y417 F417 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C524 F524 Biomuta DOID:1324 / lung cancer [ cosmic ]
R621 Q621 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
R621 W621 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T653 K653 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S654 G654 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S654 I654 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T657 I657 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
T738 K738 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T738 I738 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
T738 S738 Biomuta DOID:1324 / lung cancer [ cosmic ]
S739 P739 Biomuta DOID:363 / uterine cancer [ icgc ]
S753 F753 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2021 / placenta cancer [ cosmic ]
C792 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S853 L853 Biomuta DOID:4159 / skin cancer [ cosmic ]
S853 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S939 L939 Biomuta [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc, cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]