iPTMnet Report for P26012 (ITGB8)
Protein Information
| UniProt AC / UniProt ID | P26012 / ITB8_HUMAN |
| Protein Name | Integrin beta-8 precursor |
| Gene Name | Name: ITGB8 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P26012 |
| PRO Name | integrin beta-8 (human) |
| Definition | An integrin beta-8 that is encoded in the genome of human. |
| Short Label | hITGB8 |
| Category | organism-gene |
DAG ViewP26012 (ITGB8) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S78 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y314 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S329 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N402 | N-Glycosylation | score2 | UniProt | 31792290 | ||
| N421 | N-Glycosylation | score2 | UniProt | 31792290 | ||
| N431 | N-Glycosylation | score2 | UniProt | 31792290 | ||
| Y447 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S468 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K480 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K758 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S75 | L75 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| N421 | D421 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K480 | N480 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
