Protein Information

Cytoscape View


UniProt AC / UniProt ID P26010 / ITB7_HUMAN
Protein Name Integrin beta-7 precursor
Gene Name Name: ITGB7
Organism Homo sapiens (Human)

PRO ID PR:P26010
DAG View
PRO Name integrin beta-7 (human)
Definition An integrin beta-7 that is encoded in the genome of human.
Short Label hITGB7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P26010 (ITGB7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
N68 N-Glycosylation GlyGen 24190977
T131 Phosphorylation PhosphoSitePlus
Y150 Phosphorylation PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
N531 N-Glycosylation GlyGen 24190977
S551 Phosphorylation PhosphoSitePlus
N590 N-Glycosylation GlyGen 24190977
K642 Ubiquitination PhosphoSitePlus
K689 Ubiquitination PhosphoSitePlus
Y753 Phosphorylation Q05397 (PTK2) , P12931 (SRC) PhosphoSitePlus 16874740
Y758 Phosphorylation P12931 (SRC) , Q05397 (PTK2) PhosphoSitePlus 16874740
K763 Ubiquitination PhosphoSitePlus
K771 Ubiquitination PhosphoSitePlus
Y778 Phosphorylation PhosphoSitePlus
K779 Ubiquitination PhosphoSitePlus
S780 Phosphorylation PhosphoSitePlus
T783 Phosphorylation phospho.ELM   PhosphoSitePlus 12682249
T784 Phosphorylation PhosphoSitePlus
T785 Phosphorylation PhosphoSitePlus
S795 Phosphorylation PhosphoSitePlus
T797 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T783 Phosphorylation Q05655 (PRKCD) , P05771 (PRKCB) HPRD 12682249


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K24 N24 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
K53 * Biomuta DOID:2394 / ovarian cancer [ tcga ]
Y753 H753 Biomuta DOID:2994 / germ cell cancer [ cosmic ]
Y758 * Biomuta DOID:3571 / liver cancer [ icgc ]
Y778 * Biomuta DOID:3571 / liver cancer [ icgc ]
S780 R780 Biomuta DOID:1909 / melanoma [ tcga ]
S780 N780 Biomuta DOID:1909 / melanoma [ tcga ]