iPTMnet Report for P26010 (ITGB7)
Protein Information
| UniProt AC / UniProt ID | P26010 / ITB7_HUMAN |
| Protein Name | Integrin beta-7 precursor |
| Gene Name | Name: ITGB7 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P26010 |
| PRO Name | integrin beta-7 (human) |
| Definition | An integrin beta-7 that is encoded in the genome of human. |
| Short Label | hITGB7 |
| Category | organism-gene |
P26010 (ITGB7) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S19 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K24 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K53 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K65 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N68 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| T131 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y150 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K165 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K199 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K211 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C271 | Methylation | score1 | IEDB | 31844290 | ||
| N279 | N-Glycosylation | score2 | UniProt | 22232704 | ||
| K299 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K361 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K365 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N434 | N-Glycosylation | score2 | UniProt | 22232704 | ||
| C448 | Methylation | score1 | IEDB | 31844290 | ||
| N531 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| C537 | Methylation | score1 | IEDB | 31844290 | ||
| S551 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N590 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| K642 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C654 | Methylation | score1 | IEDB | 31844290 | ||
| C670 | Methylation | score1 | IEDB | 31844290 | ||
| K689 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y753 | Phosphorylation | Q05397 (PTK2) , P12931 (SRC) | score2 | PhosphoSitePlus | 16874740 | |
| Y758 | Phosphorylation | P12931 (SRC) , Q05397 (PTK2) | score2 | PhosphoSitePlus | 16874740 | |
| K763 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K771 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y778 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K779 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S780 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T783 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 12682249 | ||
| T784 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T785 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S795 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T797 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K24 | N24 | Biomuta | [ cosmic ] DOID:9256 / colorectal cancer [ icgc ] | |
| Y753 | H753 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
| Y758 | N758 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S780 | R780 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S780 | N780 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
DAG View