iPTMnet Report for P25940 (COL5A3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P25940 / CO5A3_HUMAN
Protein Name Collagen alpha-3(V) chain precursor
Gene Name Name: COL5A3
Organism Homo sapiens (Human)

PRO ID PR:P25940
DAG View
PRO Name collagen alpha-3(V) chain (human)
Definition A collagen alpha-3(V) chain that is encoded in the genome of human.
Short Label hCOL5A3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P25940 (COL5A3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N102 N-Glycosylation GlyGen   UniProt 29741879, 19159218
Y110 Phosphorylation PhosphoSitePlus
N141 N-Glycosylation GlyGen   UniProt 19159218
T232 O-Glycosylation GlyGen 30459171
K247 Acetylation PhosphoSitePlus
K249 Acetylation PhosphoSitePlus
K251 Acetylation PhosphoSitePlus
K254 Acetylation PhosphoSitePlus
K255 Acetylation PhosphoSitePlus
S323 O-Glycosylation GlyGen 30459171
T330 O-Glycosylation GlyGen 30459171
S349 O-Glycosylation GlyGen   UniProt 36213313
T350 O-Glycosylation GlyGen 30459171
S718 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340
S1315 Phosphorylation PhosphoSitePlus
T1684 Phosphorylation PhosphoSitePlus
T1685 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K247 Q247 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K251 Q251 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T330 S330 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S349 F349 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1684 K1684 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1684 M1684 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:3565 / meningioma [ cosmic ] DOID:1725 / peritoneum cancer [ cosmic ]