Protein Information

Cytoscape View


UniProt AC / UniProt ID P25911 / LYN_MOUSE
Protein Name Tyrosine-protein kinase Lyn
Gene Name Name: Lyn
Organism Mus musculus (Mouse)

PRO ID PR:P25911
DAG View
PRO Name tyrosine-protein kinase Lyn (mouse)
Definition A tyrosine-protein kinase Lyn that is encoded in the genome of mouse.
Short Label mLYN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P25911 (Lyn) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K9 Ubiquitination PhosphoSitePlus
S19 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19144319
K20 Ubiquitination PhosphoSitePlus
Y32 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
Y193 Phosphorylation PhosphoSitePlus   RLIMS-P 24440445
Y194 Phosphorylation PhosphoSitePlus   RLIMS-P 24440445
K213 Ubiquitination PhosphoSitePlus
Y265 Phosphorylation PhosphoSitePlus
Y266 Phosphorylation PhosphoSitePlus
T270 Phosphorylation PhosphoSitePlus
Y316 Phosphorylation PhosphoSitePlus
Y397 Phosphorylation P25911 (Lyn) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 19144319, 15504915, 10415030, ...16272347, 21183079, 24440445
T398 Phosphorylation PhosphoSitePlus
Y460 Phosphorylation PhosphoSitePlus
Y473 Phosphorylation PhosphoSitePlus
T489 Phosphorylation PhosphoSitePlus
Y501 Phosphorylation RLIMS-P 24440445
T502 Phosphorylation PhosphoSitePlus
Y508 Phosphorylation P41241 (Csk) , P25911 (Lyn) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 19144319, 15504915, 10415030, ...18034455, 24440445
Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation phospho.ELM   PhosphoSitePlus 19144319
K20 Ubiquitination PhosphoSitePlus
Y376 Phosphorylation phospho.ELM 19144319
Y487 Phosphorylation phospho.ELM 19144319


P25911 (Lyn) as PTM Enzyme



Substrate Site Score Source PMID
O70469 (Dok2) Y276 PhosphoSitePlus 10428862
O70469 (Dok2) Y304 PhosphoSitePlus 10428862
O70469 (Dok2) Y351 PhosphoSitePlus 10428862
P14753 (Epor) Y488 PhosphoSitePlus 9573010
P14753 (Epor) Y503 PhosphoSitePlus 9573010
P20491 (Fcer1g) Y65 PhosphoSitePlus 18715866
P20491 (Fcer1g) Y76 PhosphoSitePlus 18715866
P25911 (Lyn) Y397 phospho.ELM   PhosphoSitePlus   UniProt 19144319, 10415030
P25911 (Lyn) Y508 UniProt 18034455
P25918 (Cd19) Y493 Signor 10933394
P25918 (Cd19) Y522 Signor 10933394
P28867 (Prkcd) Y52 phospho.ELM 7575560
P28867 (Prkcd) Y155 phospho.ELM 7575560
P28867 (Prkcd) Y311 PhosphoSitePlus 18387943
P28867 (Prkcd) Y332 PhosphoSitePlus 18387943
P28867 (Prkcd) Y565 phospho.ELM 7575560
P29351 (Ptpn6) Y564 PhosphoSitePlus 20858858
P48025 (Syk) Y130 phospho.ELM 9820500
P48025 (Syk) Y317 phospho.ELM   PhosphoSitePlus 9820500
P48025 (Syk) Y342 phospho.ELM   PhosphoSitePlus 9820500
P48025 (Syk) Y346 phospho.ELM   PhosphoSitePlus 9820500
Q3U1F9 (Pag1) Y386 phospho.ELM   PhosphoSitePlus 16920712
Q3U1F9 (Pag1) Y414 phospho.ELM   PhosphoSitePlus 16920712
Q60598 (Cttn) Y466 PhosphoSitePlus 25825709
Q99N57 (Raf1) Y341 PhosphoSitePlus 11716471
Q99N69 (Lpxn) Y72 phospho.ELM 17640867
Q9EPK8 (Trpv4) Y253 phospho.ELM   PhosphoSitePlus 12538589