Protein Information

Cytoscape View


UniProt AC / UniProt ID P25786 / PSA1_HUMAN
Protein Name Proteasome subunit alpha type-1
Gene Name Name: PSMA1
Synonyms:HC2,NU,PROS30,PSC2;
Organism Homo sapiens (Human)

PRO ID PR:P25786
DAG View
PRO Name proteasome subunit alpha type-1 (human)
Definition A proteasome subunit alpha type-1 that is encoded in the genome of human.
Short Label hPSMA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P25786 (PSMA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K30 Ubiquitination PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
T42 Phosphorylation PhosphoSitePlus
K50 Methylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus   UniProt 23186163
S114 Phosphorylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
T116 Phosphorylation PhosphoSitePlus
T120 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
Y153 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus   UniProt 23186163
C182 S-Nitrosylation dbSNO 26338901
K189 Ubiquitination PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus
S230 Phosphorylation PhosphoSitePlus
K243 Sumoylation PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO
S14 Phosphorylation HPRD 18669648, 20068231
S54 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S20 Phosphorylation HPRD 18669648, 20068231
S60 Phosphorylation HPRD 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036310 (hPSMA1/Ac:1) acM1 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S40 * Biomuta DOID:11934 / head and neck cancer [ tcga ]
Y153 C153 Biomuta DOID:4362 / cervical cancer [ tcga ]
S160 F160 Biomuta DOID:1909 / melanoma [ icgc, tcga ]