Protein Information

Cytoscape View


UniProt AC / UniProt ID P25774 / CATS_HUMAN
Protein Name Cathepsin S precursor
Gene Name Name: CTSS
Organism Homo sapiens (Human)

PRO ID PR:P25774
DAG View
PRO Name cathepsin S (human)
Definition A cathepsin S that is encoded in the genome of human.
Short Label hCTSS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P25774 (CTSS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K42 Ubiquitination PhosphoSitePlus
N104 N-Glycosylation GlyGen   UniProt 9524075
S171 Phosphorylation PhosphoSitePlus
Y175 Phosphorylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
Y215 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
Y232 Phosphorylation PhosphoSitePlus
Y262 Phosphorylation PhosphoSitePlus
N315 N-Glycosylation GlyGen 24190977
N318 N-Glycosylation GlyGen 24190977


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S171 T171 Biomuta DOID:0070003 / blastoma [ cosmic ]
Y262 C262 Biomuta DOID:1612 / breast cancer [ tcga ]
Y262 H262 Biomuta DOID:10534 / stomach cancer [ tcga ]