iPTMnet Report P25774 CTSS

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P25774 / CATS_HUMAN
Protein Name	Cathepsin S precursor
Gene Name	Name: CTSS
Organism	Homo sapiens (Human)

PRO ID	PR:P25774 DAG View
PRO Name	cathepsin S (human)
Definition	A cathepsin S that is encoded in the genome of human.
Short Label	hCTSS
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P25774 (CTSS) as Substrate

P25774

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K42	Ubiquitination		score1	PhosphoSitePlus
	N104	N-Glycosylation		score3	GlyGen UniProt	9524075
	S171	Phosphorylation		score1	PhosphoSitePlus
	Y175	Phosphorylation		score1	PhosphoSitePlus
	S200	Phosphorylation		score1	PhosphoSitePlus
	Y215	Phosphorylation		score1	PhosphoSitePlus
	S217	Phosphorylation		score1	PhosphoSitePlus
	Y232	Phosphorylation		score1	PhosphoSitePlus
	Y262	Phosphorylation		score1	PhosphoSitePlus
	N315	N-Glycosylation		score1	GlyGen	24190977
	N318	N-Glycosylation		score1	GlyGen	24190977

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S171	T171	Biomuta		DOID:0070003 / blastoma [ cosmic ]
Y262	C262	Biomuta		DOID:1612 / breast cancer [ tcga ]
Y262	H262	Biomuta		DOID:10534 / stomach cancer [ tcga ]