Protein Information

Cytoscape View


UniProt AC / UniProt ID P25774 / CATS_HUMAN
Protein Name Cathepsin S precursor
Gene Name Name: CTSS
Organism Homo sapiens (Human)

PRO ID PR:P25774
DAG View
PRO Name cathepsin S (human)
Definition A cathepsin S that is encoded in the genome of human.
Short Label hCTSS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P25774 (CTSS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K42 Ubiquitination PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
Y175 Phosphorylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
Y215 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
Y232 Phosphorylation PhosphoSitePlus
Y262 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S171 T171 Biomuta DOID:0070003 / blastoma [ cosmic ]
Y262 C262 Biomuta DOID:1612 / breast cancer [ tcga ]
Y262 H262 Biomuta DOID:10534 / stomach cancer [ tcga ]