iPTMnet Report for P25685 (DNAJB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P25685 / DNJB1_HUMAN
Protein Name DnaJ homolog subfamily B member 1
Gene Name Name: DNAJB1
Synonyms:DNAJ1,HDJ1,HSPF1;
Organism Homo sapiens (Human)

PRO ID PR:P25685
DAG View
PRO Name DnaJ homolog subfamily B member 1 (human)
Definition A DnaJ homolog subfamily B member 1 that is encoded in the genome of human.
Short Label hDNAJB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P25685 (DNAJB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K3 Ubiquitination PhosphoSitePlus
Y5 Phosphorylation PhosphoSitePlus
R13 Methylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
K44 Acetylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
Y52 Phosphorylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
R66 Methylation PhosphoSitePlus
T88 Phosphorylation PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus
S149 Phosphorylation Q8IW41 (MAPKAPK5) PRO   PhosphoSitePlus   RLIMS-P   Signor 24309468
S151 Phosphorylation Q8IW41 (MAPKAPK5) PRO   PhosphoSitePlus   RLIMS-P   Signor 24309468
K159 Ubiquitination PhosphoSitePlus
S171 Phosphorylation Q8IW41 (MAPKAPK5) PRO   PhosphoSitePlus   RLIMS-P   Signor 24309468
Y176 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
C179 Methylation IEDB 31844290
T180 Phosphorylation PhosphoSitePlus
K181 Acetylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
K195 Acetylation PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
T205 Phosphorylation PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
T227 Phosphorylation PhosphoSitePlus
S228 Phosphorylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
Y256 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
T307 Phosphorylation PhosphoSitePlus   UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
S196 Phosphorylation HPRD 19651622
T307 Phosphorylation HPRD 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047193 (hDNAJB1/InitMet-/Phos:1) pS149,pS151,pS171 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y5 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S16 L16 Biomuta DOID:4159 / skin cancer [ cosmic ]
R66 C66 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S89 C89 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S171 F171 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K222 R222 Biomuta DOID:3571 / liver cancer [ cosmic ]
T227 N227 Biomuta DOID:3571 / liver cancer [ cosmic ]
T227 I227 Biomuta DOID:1612 / breast cancer [ cosmic ]