iPTMnet Report for P25588 (MRC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P25588 / MRC1_YEAST
Protein Name Mediator of replication checkpoint protein 1
Gene Name Name: MRC1
OrderedLocusNames:YCL061C;ORFNames:YCL61C/YCL60C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

PRO ID PR:P25588
DAG View
PRO Name mediator of replication checkpoint protein 1 (yeast)
Definition A mediator of replication checkpoint protein 1 that is encoded in the genome of yeast.
Short Label ymrc1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P25588 (MRC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T90 Phosphorylation P38111 (MEC1) , P38110 (TEL1) BioGRID 12865299, 19515819
S112 Phosphorylation SGD 33491328
Y113 Phosphorylation SGD 33491328
S114 Phosphorylation BioGRID   SGD 18407956
S120 Phosphorylation BioGRID   SGD 18407956
S121 Phosphorylation BioGRID   SGD 20190278, 33481703, 33491328, ...18407956, 23749301
T123 Phosphorylation P38110 (TEL1) , P38111 (MEC1) BioGRID   SGD 12865299, 19515819, 18407956
S144 Phosphorylation BioGRID   SGD   UniProt 33491328, 18407956
T151 Phosphorylation P38110 (TEL1) , P38111 (MEC1) BioGRID 12865299, 19515819
S164 Phosphorylation P38111 (MEC1) , P38110 (TEL1) BioGRID 12865299, 19515819
T169 Phosphorylation SGD 29371596
T179 Phosphorylation P38110 (TEL1) , P38111 (MEC1) BioGRID 12865299, 19515819
S184 Phosphorylation BioGRID   SGD 33481703, 33491328, 18407956, ...23749301
S185 Phosphorylation SGD 33491328
S189 Phosphorylation P38110 (TEL1) , P38111 (MEC1) BioGRID   SGD 20190278, 12865299, 33491328, ...19515819
T191 Phosphorylation BioGRID   SGD 18407956
S207 Phosphorylation BioGRID   SGD 21177495, 33481703, 18407956
S211 Phosphorylation SGD 33491328
S215 Phosphorylation BioGRID   SGD 33481703, 29371596, 18407956, ...23749301, 21177495, 33491328
S229 Phosphorylation SGD 29371596, 33491328
T242 Phosphorylation P38110 (TEL1) , P38111 (MEC1) BioGRID 12865299, 19515819
T272 Phosphorylation P38110 (TEL1) , P38111 (MEC1) BioGRID 12865299, 19515819
S300 Phosphorylation SGD 33491328
S367 Phosphorylation SGD 33481703, 33491328
T373 Phosphorylation SGD 33481703, 33491328
S409 Phosphorylation BioGRID   SGD   UniProt 19779198
S411 Phosphorylation BioGRID   SGD   UniProt 19779198
S434 Phosphorylation P38111 (MEC1) , P38110 (TEL1) BioGRID   SGD   UniProt 12865299, 19515819, 18407956
K498 Sumoylation SGD 33502312
S559 Phosphorylation SGD 33491328
S579 Phosphorylation BioGRID   SGD 20702584, 33481703
S581 Phosphorylation BioGRID   SGD 20702584, 33481703
S605 Phosphorylation BioGRID   SGD   UniProt 19795423, 19823750, 17563356, ...17330950, 32597660, 20702584, 18407956, 17287358, 19779198, 30516470, 19684113, 21177495, 33491328, 33481703
S607 Phosphorylation BioGRID   SGD   UniProt 19795423, 30516470, 33481703, ...17563356, 17330950, 20702584, 18407956, 19779198, 19684113, 21177495, 33491328, 19823750
T609 Phosphorylation BioGRID   SGD   UniProt 19795423, 33481703, 17287358, ...19779198, 19684113, 21177495, 33491328, 19823750
S622 Phosphorylation BioGRID   SGD 18407956, 33491328, 17563356
T653 Phosphorylation P38111 (MEC1) , P38110 (TEL1) BioGRID 12865299
T665 Phosphorylation SGD 33491328
S801 Phosphorylation BioGRID   UniProt 19779198, 18407956
S807 Phosphorylation BioGRID   SGD   UniProt 19779198, 33491328, 18407956
T882 Phosphorylation P38111 (MEC1) , P38110 (TEL1) BioGRID 12865299
S911 Phosphorylation BioGRID   SGD   UniProt 33491328, 18407956
S920 Phosphorylation SGD 33491328
S924 Phosphorylation SGD 33491328
S958 Phosphorylation SGD 33491328
S961 Phosphorylation SGD 23749301, 33491328
T963 Phosphorylation SGD 33491328
S965 Phosphorylation P38110 (TEL1) , P38111 (MEC1) BioGRID   SGD 33481703, 32597660, 18407956, ...23749301, 12865299, 33491328
T967 Phosphorylation SGD 33491328
S969 Phosphorylation SGD 33491328
S997 Phosphorylation SGD 33481703
S1013 Phosphorylation SGD 33491328
S1093 Phosphorylation SGD 33481703, 18407956, 33491328