iPTMnet Report for P25391 (LAMA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P25391 / LAMA1_HUMAN
Protein Name Laminin subunit alpha-1 precursor
Gene Name Name: LAMA1
Synonyms:LAMA;
Organism Homo sapiens (Human)

PRO ID PR:P25391
DAG View
PRO Name laminin subunit alpha-1 (human)
Definition A laminin subunit alpha-1 that is encoded in the genome of human.
Short Label hLAMA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P25391 (LAMA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S31 Phosphorylation PhosphoSitePlus
Y337 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
T351 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983
C361 Methylation IEDB 31844290
K486 Acetylation PhosphoSitePlus
Y490 Phosphorylation PhosphoSitePlus
K538 Ubiquitination PhosphoSitePlus
S553 Phosphorylation PhosphoSitePlus
N555 N-Glycosylation GlyGen 23090970, 24190977
T581 Phosphorylation PhosphoSitePlus
K651 Ubiquitination PhosphoSitePlus
Y683 Phosphorylation PhosphoSitePlus
Y890 Phosphorylation PhosphoSitePlus
T895 Phosphorylation PhosphoSitePlus
K897 Ubiquitination PhosphoSitePlus
S1299 Phosphorylation PhosphoSitePlus
K1303 Ubiquitination PhosphoSitePlus
T1306 Phosphorylation PhosphoSitePlus
K1384 Ubiquitination PhosphoSitePlus
T1426 Phosphorylation PhosphoSitePlus
S1436 Phosphorylation PhosphoSitePlus
Y1439 Phosphorylation PhosphoSitePlus
T1501 Phosphorylation PhosphoSitePlus
K1616 Acetylation PhosphoSitePlus
K1618 Ubiquitination PhosphoSitePlus
K1631 Ubiquitination PhosphoSitePlus
K1642 Ubiquitination PhosphoSitePlus
K1738 Ubiquitination PhosphoSitePlus
K1747 Ubiquitination PhosphoSitePlus
K1756 Ubiquitination PhosphoSitePlus
K1762 Ubiquitination PhosphoSitePlus
K1796 Ubiquitination PhosphoSitePlus
K1840 Ubiquitination PhosphoSitePlus
K1953 Ubiquitination PhosphoSitePlus
K1961 Ubiquitination PhosphoSitePlus
N1991 N-Glycosylation GlyGen 23090970, 24190977
K2012 Ubiquitination PhosphoSitePlus
T2039 Phosphorylation HPRD 20068231
S2040 Phosphorylation HPRD 20068231
S2042 Phosphorylation HPRD 20068231
K2089 Ubiquitination PhosphoSitePlus
N2098 N-Glycosylation GlyGen 29741879
K2103 Ubiquitination PhosphoSitePlus
T2187 Phosphorylation PhosphoSitePlus
N2243 N-Glycosylation GlyGen   UniProt 19159218
K2264 Ubiquitination PhosphoSitePlus
K2269 Ubiquitination PhosphoSitePlus
C2294 Methylation IEDB 31844290
N2384 N-Glycosylation GlyGen 23090970, 24190977
R2428 Methylation PhosphoSitePlus
K2431 Ubiquitination PhosphoSitePlus
S2474 Phosphorylation PhosphoSitePlus
Y2475 Phosphorylation PhosphoSitePlus
K2479 Methylation PhosphoSitePlus
S2615 Phosphorylation PhosphoSitePlus
K2689 Ubiquitination PhosphoSitePlus
K2785 Ubiquitination PhosphoSitePlus
K2796 Ubiquitination PhosphoSitePlus
K2801 Ubiquitination PhosphoSitePlus
K2849 Ubiquitination PhosphoSitePlus
N2852 N-Glycosylation GlyGen 23090970, 24190977
K2869 Ubiquitination PhosphoSitePlus
K2873 Ubiquitination PhosphoSitePlus
S2875 Phosphorylation PhosphoSitePlus
T2922 Phosphorylation PhosphoSitePlus
S2933 Phosphorylation PhosphoSitePlus
K2976 Ubiquitination PhosphoSitePlus
K2984 Ubiquitination PhosphoSitePlus
S3048 Phosphorylation PhosphoSitePlus
S3053 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S31 N31 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K486 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K651 T651 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K897 M897 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S1299 F1299 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1306 M1306 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K1631 R1631 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K1756 Q1756 Biomuta DOID:1612 / breast cancer [ cosmic ]
K1796 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
T2039 R2039 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
C2294 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R2428 S2428 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K2431 N2431 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S2474 A2474 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2474 F2474 Biomuta DOID:4159 / skin cancer [ cosmic ]
K2479 N2479 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S2615 N2615 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K2801 N2801 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K2849 N2849 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K2873 N2873 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K2984 E2984 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S3048 G3048 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]