iPTMnet Report for P25106 (ACKR3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P25106 / ACKR3_HUMAN
Protein Name Atypical chemokine receptor 3
Gene Name Name: ACKR3
Synonyms:CMKOR1,CXCR7;
Organism Homo sapiens (Human)

PRO ID PR:P25106
DAG View
PRO Name atypical chemokine receptor 3 (human)
Definition An atypical chemokine receptor 3 that is encoded in the genome of human.
Short Label hACKR3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P25106 (ACKR3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K328 Ubiquitination PhosphoSitePlus
Y334 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
T338 Phosphorylation PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
S350 Phosphorylation HPRD   PhosphoSitePlus 19664994
T352 Phosphorylation PhosphoSitePlus   RLIMS-P 33799570
Y354 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus   RLIMS-P 33799570
S360 Phosphorylation PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S335 L335 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S347 F347 Biomuta DOID:4159 / skin cancer [ cosmic ]
T352 M352 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc, tcga ]
S355 Y355 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S360 I360 Biomuta DOID:1319 / brain cancer [ cosmic ]