iPTMnet Report for P25100 (ADRA1D)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P25100 / ADA1D_HUMAN
Protein Name Alpha-1D adrenergic receptor
Gene Name Name: ADRA1D
Synonyms:ADRA1A;
Organism Homo sapiens (Human)

PRO ID PR:P25100
DAG View
PRO Name alpha-1D adrenergic receptor (human)
Definition An alpha-1D adrenergic receptor that is encoded in the genome of human.
Short Label hADRA1D
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P25100 (ADRA1D) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S201 Phosphorylation PhosphoSitePlus
S228 Phosphorylation PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
T328 Phosphorylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
S332 Phosphorylation PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus
T442 Phosphorylation PhosphoSitePlus
T477 Phosphorylation PhosphoSitePlus
S486 Phosphorylation PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus
T507 Phosphorylation PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
S518 Phosphorylation PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S228 F228 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S323 R323 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S332 L332 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S334 F334 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S492 R492 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T507 M507 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S543 F543 Biomuta DOID:4159 / skin cancer [ cosmic ]