iPTMnet Report for P25024 (CXCR1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P25024 / CXCR1_HUMAN
Protein Name C-X-C chemokine receptor type 1
Gene Name Name: CXCR1
Synonyms:CMKAR1,IL8RA;
Organism Homo sapiens (Human)

PRO ID PR:P25024
DAG View
PRO Name C-X-C chemokine receptor type 1 (human)
Definition A C-X-C chemokine receptor type 1 that is encoded in the genome of human.
Short Label hCXCR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P25024 (CXCR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R279 Methylation PhosphoSitePlus
R280 Methylation PhosphoSitePlus
T290 O-Glycosylation GlyGen 34105348
S298 O-Glycosylation GlyGen 34105348


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R279 C279 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
R279 H279 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
R280 H280 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R280 C280 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ]