Protein Information

Cytoscape View


UniProt AC / UniProt ID P24855 / DNAS1_HUMAN
Protein Name Deoxyribonuclease-1 precursor
Gene Name Name: DNASE1
Synonyms:DNL1,DRNI;
Organism Homo sapiens (Human)

PRO ID PR:P24855
DAG View
PRO Name deoxyribonuclease-1 (human)
Definition A deoxyribonuclease-1 that is encoded in the genome of human.
Short Label hDNASE1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P24855 (DNASE1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S39 Phosphorylation PhosphoSitePlus
N40 N-Glycosylation GlyGen   UniProt 2277032, 30237853
T42 Phosphorylation PhosphoSitePlus
Y46 Phosphorylation PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
C231 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N40 S40 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T42 A42 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C231 R231 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]