iPTMnet Report for P24821 (TNC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P24821 / TENA_HUMAN
Protein Name Tenascin precursor
Gene Name Name: TNC
Synonyms:HXB;
Organism Homo sapiens (Human)

PRO ID PR:P24821
DAG View
PRO Name tenascin (human)
Definition A tenascin that is encoded in the genome of human.
Short Label hTNC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P24821 (TNC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N38 N-Glycosylation GlyGen 23090970, 32125861, 24190977
S62 Phosphorylation PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus   UniProt 24275569
S70 Phosphorylation PhosphoSitePlus   UniProt 24275569
S72 O-Glycosylation GlyGen   UniProt 36213313
S72 Phosphorylation PhosphoSitePlus   UniProt 26091039, 24275569
S81 O-Glycosylation GlyGen 30459171
S81 Phosphorylation PhosphoSitePlus
S84 O-Glycosylation GlyGen 30459171
T91 O-Glycosylation GlyGen 30459171
T91 Phosphorylation PhosphoSitePlus
N166 N-Glycosylation GlyGen 23090970, 29741879, 32125861, ...24190977
N184 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 18780401, ...32125861, 24190977
S257 Phosphorylation PhosphoSitePlus
N327 N-Glycosylation GlyGen 23090970, 29741879, 32125861, ...24190977
Y491 Phosphorylation PhosphoSitePlus
S616 Phosphorylation PhosphoSitePlus
Y688 Phosphorylation IEDB 35494241
K719 Acetylation PhosphoSitePlus
N788 N-Glycosylation GlyGen 23090970, 24190977
T800 Phosphorylation PhosphoSitePlus
S903 Phosphorylation PhosphoSitePlus
T905 Phosphorylation PhosphoSitePlus   UniProt 24275569
K942 Ubiquitination PhosphoSitePlus
T1007 Phosphorylation PhosphoSitePlus
N1018 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...32125861, 24190977
Y1019 Phosphorylation PhosphoSitePlus
S1020 Phosphorylation PhosphoSitePlus
T1023 Phosphorylation PhosphoSitePlus
N1034 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
T1035 O-Glycosylation GlyGen 23301498, 28657654
S1037 O-Glycosylation GlyGen 23301498, 28657654
N1079 N-Glycosylation GlyGen   UniProt 29391424, 18780401
N1093 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 24190977, ...32125861, 18780401
N1119 N-Glycosylation GlyGen 23090970, 29741879, 29391424, ...32125861, 24190977
N1184 N-Glycosylation GlyGen   UniProt 19159218
N1210 N-Glycosylation GlyGen 29741879
N1261 N-Glycosylation GlyGen   UniProt 18780401
T1265 O-Glycosylation GlyGen 30459171
N1275 N-Glycosylation GlyGen   UniProt 19159218
N1301 N-Glycosylation GlyGen   UniProt 19159218, 18780401
S1310 Phosphorylation PhosphoSitePlus
N1366 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 32125861
N1392 N-Glycosylation GlyGen 23090970, 29741879, 29391424, ...32125861, 24190977
Y1418 Phosphorylation PhosphoSitePlus
T1469 O-Glycosylation GlyGen 30459171
N1485 N-Glycosylation GlyGen   UniProt 32125861, 19159218, 24190977, ...23090970, 29391424, 18780401, 29741879
T1492 Phosphorylation PhosphoSitePlus
T1502 Phosphorylation PhosphoSitePlus
S1699 Phosphorylation PhosphoSitePlus
T1701 Phosphorylation PhosphoSitePlus
S1703 Phosphorylation PhosphoSitePlus
T1751 Phosphorylation PhosphoSitePlus
T1760 Phosphorylation PhosphoSitePlus
Y1775 Phosphorylation PhosphoSitePlus
S1778 Phosphorylation PhosphoSitePlus
N1809 N-Glycosylation GlyGen   UniProt 16335952, 29741879
T1825 O-Glycosylation GlyGen 30459171
T1842 Phosphorylation PhosphoSitePlus
T1844 Phosphorylation PhosphoSitePlus
S1846 Phosphorylation PhosphoSitePlus
T1878 Phosphorylation PhosphoSitePlus
K1882 Ubiquitination PhosphoSitePlus
T1885 Phosphorylation PhosphoSitePlus
S1889 Phosphorylation PhosphoSitePlus
T1902 Phosphorylation PhosphoSitePlus
T1906 Phosphorylation PhosphoSitePlus
Y2070 Phosphorylation PhosphoSitePlus
T2129 Phosphorylation PhosphoSitePlus
T2134 Phosphorylation PhosphoSitePlus
N2162 N-Glycosylation GlyGen   UniProt 18780401
Site PTM Type PTM Enzyme Score Source PMID
S72 Phosphorylation HPRD 18578522
T1902 Phosphorylation HPRD 20166139
T1906 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S62 F62 Biomuta [ cosmic ]
S65 L65 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S70 L70 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S81 L81 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S84 C84 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S903 F903 Biomuta DOID:4159 / skin cancer [ cosmic ]
K942 N942 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
N1018 S1018 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y1019 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1037 F1037 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
N1119 I1119 Biomuta DOID:3571 / liver cancer [ cosmic ]
N1261 K1261 Biomuta DOID:10534 / stomach cancer [ cosmic ]
N1301 S1301 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S1310 F1310 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T1469 A1469 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T1502 I1502 Biomuta [ cosmic ]
T1751 I1751 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T1760 A1760 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
Y1775 F1775 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T1825 I1825 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
T1842 A1842 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1844 A1844 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1878 A1878 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T1885 A1885 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1889 F1889 Biomuta DOID:4159 / skin cancer [ cosmic ]