iPTMnet Report for P24666 (ACP1)
Protein Information
UniProt AC / UniProt ID | P24666 / PPAC_HUMAN |
Protein Name | Low molecular weight phosphotyrosine protein phosphatase |
Gene Name | Name: ACP1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P24666 |
PRO Name | low molecular weight phosphotyrosine protein phosphatase (human) |
Definition | A low molecular weight phosphotyrosine protein phosphatase that is encoded in the genome of human. |
Short Label | hACP1 |
Category | organism-gene |
P24666 (ACP1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score2 | UniProt | 1939112 | ||
S8 | Phosphorylation | score1 | PhosphoSitePlus | |||
S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
K29 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y50 | Phosphorylation | score1 | PhosphoSitePlus | |||
S62 | Phosphorylation | score1 | PhosphoSitePlus | |||
R66 | Methylation | score1 | PhosphoSitePlus | |||
T79 | Phosphorylation | score1 | PhosphoSitePlus | |||
K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
T85 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y88 | Phosphorylation | score1 | PhosphoSitePlus | |||
K113 | Sumoylation | score1 | PhosphoSitePlus | |||
K113 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y120 | Phosphorylation | score1 | PhosphoSitePlus | |||
K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y132 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 10452533, 9038134, 16890200, ... | ||
Y132 | Phosphorylation | P06239 (LCK) | score2 | PhosphoSitePlus | 9038134 | |
Y133 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 9038134 | ||
Y133 | Phosphorylation | P06239 (LCK) | score2 | PhosphoSitePlus | 9038134 | |
S137 | Phosphorylation | score1 | PhosphoSitePlus | |||
T141 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y143 | Phosphorylation | score1 | PhosphoSitePlus | |||
K156 | Acetylation | score1 | PhosphoSitePlus | |||
K156 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S20 | Phosphorylation | score0 | HPRD | 20068231 | ||
T32 | Phosphorylation | score0 | HPRD | 20068231 | ||
Y132 | Phosphorylation | score0 | HPRD | 17016520, 15951569 | ||
Y133 | Phosphorylation | score1 | HPRD | 9038134 | ||
Y133 | Phosphorylation | P06239 (LCK) | score1 | HPRD | 9038134 | |
Y133 | Phosphorylation | P06241 (FYN) | score1 | HPRD | 9038134 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S20 | Phosphorylation | score0 | HPRD | 20068231 | ||
S62 | Phosphorylation | score1 | PhosphoSitePlus | |||
K74 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y132 | Phosphorylation | score2 | HPRD | 17016520, 9038134 | ||
Y132 | Phosphorylation | P06239 (LCK) | score2 | HPRD | 17016520, 9038134 | |
Y132 | Phosphorylation | P06241 (FYN) | score2 | HPRD | 17016520, 9038134 | |
Y133 | Phosphorylation | score1 | HPRD | 9038134 | ||
Y133 | Phosphorylation | P06239 (LCK) | score1 | HPRD | 9038134 | |
Y133 | Phosphorylation | P06241 (FYN) | score1 | HPRD | 9038134 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S8 | Y8 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S20 | L20 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
Y50 | H50 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y120 | C120 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K124 | T124 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
Y132 | C132 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
S137 | C137 | Biomuta | DOID:1540 / parathyroid carcinoma [ cosmic ] | |
T141 | M141 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] |