iPTMnet Report for P24592 (IGFBP6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P24592 / IBP6_HUMAN
Protein Name Insulin-like growth factor-binding protein 6 precursor
Gene Name Name: IGFBP6
Synonyms:IBP6;
Organism Homo sapiens (Human)

PRO ID PR:P24592
DAG View
PRO Name insulin-like growth factor-binding protein 6 (human)
Definition An insulin-like growth factor-binding protein 6 that is encoded in the genome of human.
Short Label hIGFBP6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P24592 (IGFBP6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S120 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T126 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 30237853, 30459171, 25813380, ...23234360, 19838169, 9572875, 23584533, 26598643
T143 O-Glycosylation GlyGen 25813380
S144 O-Glycosylation GlyGen 25813380
T145 O-Glycosylation GlyGen 30459171, 25813380
T146 O-Glycosylation GlyGen 30459171, 25813380
S152 O-Glycosylation GlyGen 30459171, 25813380
T176 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T184 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S204 O-Glycosylation GlyGen   PhosphoSitePlus 21548981
S204 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
T236 O-Glycosylation GlyGen 25813380


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T146 M146 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S152 F152 Biomuta DOID:4159 / skin cancer [ cosmic ]
S152 Y152 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S204 F204 Biomuta DOID:4159 / skin cancer [ cosmic ]