iPTMnet Report for P24522 (GADD45A)
Protein Information
| UniProt AC / UniProt ID | P24522 / GA45A_HUMAN |
| Protein Name | Growth arrest and DNA damage-inducible protein GADD45 alpha |
| Gene Name | Name: GADD45A Synonyms:DDIT1,GADD45; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P24522 |
| PRO Name | growth arrest and DNA damage-inducible protein GADD45 alpha (human) |
| Definition | A growth arrest and DNA damage-inducible protein GADD45 alpha that is encoded in the genome of human. |
| Short Label | hGADD45A |
| Category | organism-gene |
DAG ViewP24522 (GADD45A) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T2 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K12 | Sumoylation | score1 | PhosphoSitePlus | |||
| K12 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K18 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K29 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S32 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y41 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C124 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T2 | N2 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K18 | N18 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| K18 | T18 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
