iPTMnet Report for P24386 (CHM)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P24386 / RAE1_HUMAN
Protein Name Rab proteins geranylgeranyltransferase component A 1
Gene Name Name: CHM
Synonyms:REP1,TCD;
Organism Homo sapiens (Human)

PRO ID PR:P24386
DAG View
PRO Name Rab proteins geranylgeranyltransferase component A 1 (human)
Definition A Rab proteins geranylgeranyltransferase component A 1 that is encoded in the genome of human.
Short Label hCHM
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P24386 (CHM) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S39 Phosphorylation PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
Y237 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
Y254 Phosphorylation PhosphoSitePlus
Y305 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
C399 Methylation IEDB 31844290
S403 O-Glycosylation GlyGen 30620550
T466 Phosphorylation PhosphoSitePlus
S468 Phosphorylation PhosphoSitePlus
T484 Phosphorylation PhosphoSitePlus
S494 Phosphorylation PhosphoSitePlus
S495 Phosphorylation PhosphoSitePlus
S651 Phosphorylation PhosphoSitePlus
S652 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y237 Phosphorylation HPRD 19562805
Y305 Phosphorylation HPRD 17287340
S651 Phosphorylation HPRD 19413330, 20068231
S652 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S39 L39 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K222 T222 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y237 H237 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S238 Y238 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S403 L403 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T484 I484 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]