iPTMnet Report for P24298 (GPT)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P24298 / ALAT1_HUMAN
Protein Name Alanine aminotransferase 1
Gene Name Name: GPT
Synonyms:AAT1,GPT1;
Organism Homo sapiens (Human)

PRO ID PR:P24298
DAG View
PRO Name alanine aminotransferase 1 (human)
Definition An alanine aminotransferase 1 that is encoded in the genome of human.
Short Label hGPT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P24298 (GPT) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation PRO   UniProt 1931970
T22 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y35 Phosphorylation PhosphoSitePlus
T61 Phosphorylation PhosphoSitePlus
T178 Phosphorylation PhosphoSitePlus
K290 Acetylation PhosphoSitePlus
Y300 Phosphorylation HPRD   PhosphoSitePlus 20068231
S311 Phosphorylation HPRD 20068231
T312 Phosphorylation HPRD 20068231
S313 Phosphorylation HPRD 20068231
Y316 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y413 Phosphorylation PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus
Y464 Phosphorylation PhosphoSitePlus
S485 Phosphorylation HPRD   PhosphoSitePlus 20068231
S496 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000035943 (hGPT/InitMet-/AcPyrdox:1) acA2 PRO 1931970


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T178 I178 Biomuta DOID:10534 / stomach cancer [ icgc ]
S311 C311 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S313 P313 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S313 C313 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]