Protein Information

Cytoscape View


UniProt AC / UniProt ID P23786 / CPT2_HUMAN
Protein Name Carnitine O-palmitoyltransferase 2, mitochondrial precursor
Gene Name Name: CPT2
Synonyms:CPT1;
Organism Homo sapiens (Human)

PRO ID PR:P23786
DAG View
PRO Name carnitine O-palmitoyltransferase 2, mitochondrial (human)
Definition A carnitine O-palmitoyltransferase 2, mitochondrial that is encoded in the genome of human.
Short Label hCPT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P23786 (CPT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T42 Phosphorylation HPRD 20068231
Y45 Phosphorylation HPRD 20068231
R51 Methylation PhosphoSitePlus
T60 Phosphorylation HPRD   PhosphoSitePlus 20068231
K69 Acetylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
K79 Acetylation PhosphoSitePlus
S126 Phosphorylation HPRD   PhosphoSitePlus 20068231
S158 Phosphorylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
S197 Phosphorylation HPRD 20068231
S198 Phosphorylation HPRD 20068231
Y202 Phosphorylation HPRD 20068231
S215 Phosphorylation HPRD 20068231
Y217 Phosphorylation HPRD   PhosphoSitePlus 20068231
S223 Phosphorylation HPRD   PhosphoSitePlus 20068231
T224 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y290 Phosphorylation PhosphoSitePlus
K433 Acetylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
T491 Phosphorylation PhosphoSitePlus
Y508 Phosphorylation PhosphoSitePlus
K510 Acetylation PhosphoSitePlus
K510 Methylation PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus
K544 Acetylation PhosphoSitePlus
R554 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K79 R79 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K182 R182 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S215 P215 Biomuta DOID:263 / kidney cancer [ cosmic ]
Y217 C217 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T224 A224 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y290 H290 Biomuta DOID:1319 / brain cancer [ cosmic ]
K510 Q510 Biomuta DOID:4159 / skin cancer [ cosmic ]
R554 Q554 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R554 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]