iPTMnet Report for P23786 (CPT2)
Protein Information
UniProt AC / UniProt ID | P23786 / CPT2_HUMAN |
Protein Name | Carnitine O-palmitoyltransferase 2, mitochondrial precursor |
Gene Name | Name: CPT2 Synonyms:CPT1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P23786 |
PRO Name | carnitine O-palmitoyltransferase 2, mitochondrial (human) |
Definition | A carnitine O-palmitoyltransferase 2, mitochondrial that is encoded in the genome of human. |
Short Label | hCPT2 |
Category | organism-gene |
P23786 (CPT2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T42 | Phosphorylation | score0 | HPRD | 20068231 | ||
Y45 | Phosphorylation | score0 | HPRD | 20068231 | ||
R51 | Methylation | score1 | PhosphoSitePlus | |||
T60 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
K69 | Acetylation | score1 | PhosphoSitePlus | |||
K69 | Ubiquitination | score1 | PhosphoSitePlus | |||
K79 | Acetylation | score1 | PhosphoSitePlus | |||
S126 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S158 | Phosphorylation | score1 | PhosphoSitePlus | |||
K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
S197 | Phosphorylation | score0 | HPRD | 20068231 | ||
S198 | Phosphorylation | score0 | HPRD | 20068231 | ||
Y202 | Phosphorylation | score0 | HPRD | 20068231 | ||
S215 | Phosphorylation | score0 | HPRD | 20068231 | ||
Y217 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S223 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
T224 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
Y290 | Phosphorylation | score1 | PhosphoSitePlus | |||
K433 | Acetylation | score1 | PhosphoSitePlus | |||
S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
T491 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y508 | Phosphorylation | score1 | PhosphoSitePlus | |||
K510 | Acetylation | score1 | PhosphoSitePlus | |||
K510 | Methylation | score1 | PhosphoSitePlus | |||
S513 | Phosphorylation | score1 | PhosphoSitePlus | |||
K544 | Acetylation | score1 | PhosphoSitePlus | |||
R554 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K79 | R79 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
K182 | R182 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S215 | P215 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
Y217 | C217 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T224 | A224 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y290 | H290 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
K510 | Q510 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
R554 | Q554 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R554 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |