iPTMnet Report for P23786 (CPT2)
Protein Information
| UniProt AC / UniProt ID | P23786 / CPT2_HUMAN |
| Protein Name | Carnitine O-palmitoyltransferase 2, mitochondrial precursor |
| Gene Name | Name: CPT2 Synonyms:CPT1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P23786 |
| PRO Name | carnitine O-palmitoyltransferase 2, mitochondrial (human) |
| Definition | A carnitine O-palmitoyltransferase 2, mitochondrial that is encoded in the genome of human. |
| Short Label | hCPT2 |
| Category | organism-gene |
P23786 (CPT2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T42 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y45 | Phosphorylation | score0 | HPRD | 20068231 | ||
| R51 | Methylation | score1 | PhosphoSitePlus | |||
| T60 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| K69 | Acetylation | score1 | PhosphoSitePlus | |||
| K69 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K79 | Acetylation | score1 | PhosphoSitePlus | |||
| S126 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| S158 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S197 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S198 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y202 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S215 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y217 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| S223 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| T224 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| Y290 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K433 | Acetylation | score1 | PhosphoSitePlus | |||
| S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T491 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y508 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K510 | Acetylation | score1 | PhosphoSitePlus | |||
| K510 | Methylation | score1 | PhosphoSitePlus | |||
| S513 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K544 | Acetylation | score1 | PhosphoSitePlus | |||
| R554 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K79 | R79 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
| K182 | R182 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S215 | P215 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| Y217 | C217 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| T224 | A224 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y290 | H290 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| K510 | Q510 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| R554 | Q554 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| R554 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View