iPTMnet Report P23771 GATA3

UniProt AC / UniProt ID	P23771 / GATA3_HUMAN
Protein Name	Trans-acting T-cell-specific transcription factor GATA-3
Gene Name	Name: GATA3
Organism	Homo sapiens (Human)

PRO ID	PR:P23771 DAG View
PRO Name	trans-acting T-cell-specific transcription factor GATA-3 (human)
Definition	A trans-acting T-cell-specific transcription factor GATA-3 that is encoded in the genome of human.
Short Label	hGATA3
Category	organism-gene

	Select/align proteoforms across species

Expanded View

Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Ubiquitination		score1	PRO
S110	Phosphorylation		score1	PhosphoSitePlus
S115	Phosphorylation		score2	PhosphoSitePlus UniProt	19690332
T156	Phosphorylation	P24941 (CDK2)	score2	PhosphoSitePlus	24820417
S162	Phosphorylation		score2	PhosphoSitePlus UniProt	19690332
S166	Phosphorylation		score1	PhosphoSitePlus
S172	Phosphorylation		score1	PhosphoSitePlus
Y186	Phosphorylation		score1	PhosphoSitePlus
K195	Ubiquitination		score1	PhosphoSitePlus
R261	Methylation		score1	PhosphoSitePlus
T271	Phosphorylation		score1	PhosphoSitePlus
Y282	Phosphorylation		score1	PhosphoSitePlus
Y290	Phosphorylation		score1	PhosphoSitePlus
K292	Acetylation		score1	PhosphoSitePlus
K304	Acetylation		score1	PhosphoSitePlus
S308	Phosphorylation	P17612 (PRKACA)	score4	neXtProt PhosphoSitePlus RLIMS-P	16109788, 28498822, 25479686, ...27053161
T315	Phosphorylation		score0	RLIMS-P	27053161
S316	Phosphorylation		score0	RLIMS-P	27053161
T323	O-Glycosylation		score1	GlyGen	32574038
Y344	Phosphorylation		score1	PhosphoSitePlus
K346	Acetylation		score1	PhosphoSitePlus
S369	Phosphorylation		score1	PhosphoSitePlus
K371	Acetylation		score1	PhosphoSitePlus
K373	Acetylation		score1	PhosphoSitePlus
K374	Acetylation		score1	PhosphoSitePlus
K376	Acetylation		score1	PhosphoSitePlus
K377	Ubiquitination		score1	PhosphoSitePlus
S381	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S258	Phosphorylation		score1	PhosphoSitePlus
	K305	Acetylation	PR:Q09472 (hEP300)	score2	PRO	10970860

	PRO ID (Short Label)	Sites	PTM Enzyme	Source	PMID
	PR:000047511 (hGATA3/UbiqLys+)	ub		PRO
	PR:000028668 (hGATA3/iso:2/Ac:1)	acK305	PR:Q09472 (hEP300)	PRO	10970860

Site	Variant	Source	Disease [Sample source]
S110	F110	Biomuta	DOID:4159 / skin cancer [ cosmic ]
T156	P156	Biomuta	DOID:1324 / lung cancer [ cosmic ]
S162	F162	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S166	L166	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
S166	A166	Biomuta	DOID:2531 / hematologic cancer [ cosmic ]
S172	L172	Biomuta	DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
K195	R195	Biomuta	DOID:1612 / breast cancer [ cosmic ]
T271	N271	Biomuta	[ cosmic ] DOID:1115 / sarcoma [ icgc ]
Y282	C282	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
K292	E292	Biomuta	DOID:1324 / lung cancer [ cosmic ]
S308	A308	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S308	Y308	Biomuta	DOID:5041 / esophageal cancer [ cosmic ]
T315	A315	Biomuta	DOID:2531 / hematologic cancer [ cosmic ]
T315	M315	Biomuta	DOID:9256 / colorectal cancer [ cosmic, icgc ]
S316	F316	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
K346	N346	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
K346	*	Biomuta	DOID:1612 / breast cancer [ cosmic ]
S369	Y369	Biomuta	DOID:1324 / lung cancer [ cosmic ]
K373	*	Biomuta	DOID:1324 / lung cancer [ cosmic ]
K376	N376	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
K377	*	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S381	*	Biomuta	DOID:1324 / lung cancer [ cosmic ]

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iPTMnet Report for P23771 (GATA3)