iPTMnet Report for P23634 (ATP2B4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P23634 / AT2B4_HUMAN
Protein Name Plasma membrane calcium-transporting ATPase 4
Gene Name Name: ATP2B4
Synonyms:ATP2B2,MXRA1;
Organism Homo sapiens (Human)

PRO ID PR:P23634
DAG View
PRO Name plasma membrane calcium-transporting ATPase 4 (human)
Definition A plasma membrane calcium-transporting ATPase 4 that is encoded in the genome of human.
Short Label hATP2B4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P23634 (ATP2B4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S17 Phosphorylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
Y216 Phosphorylation PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
S258 O-Glycosylation GlyGen 28510447, 33465208, 29351928
K314 Ubiquitination PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus   UniProt 23186163
K337 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
T415 Phosphorylation PhosphoSitePlus
Y435 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus
K523 Ubiquitination PhosphoSitePlus
C537 S-Nitrosylation dbSNO 26338901
K547 Ubiquitination PhosphoSitePlus
K561 Ubiquitination PhosphoSitePlus
K564 Ubiquitination PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
R572 Methylation PhosphoSitePlus
S576 Phosphorylation PhosphoSitePlus
T577 Phosphorylation PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
K615 Ubiquitination PhosphoSitePlus
C632 S-Nitrosylation dbSNO 26338901
K686 Ubiquitination PhosphoSitePlus
T691 Phosphorylation PhosphoSitePlus
K709 Ubiquitination PhosphoSitePlus
K725 Ubiquitination PhosphoSitePlus
K735 Ubiquitination PhosphoSitePlus
K742 Ubiquitination PhosphoSitePlus
K745 Ubiquitination PhosphoSitePlus
S757 Phosphorylation PhosphoSitePlus
T759 Phosphorylation PhosphoSitePlus
K761 Ubiquitination PhosphoSitePlus
T763 Phosphorylation PhosphoSitePlus
S771 Phosphorylation PhosphoSitePlus
T783 Phosphorylation PhosphoSitePlus
T787 Phosphorylation PhosphoSitePlus
K794 Ubiquitination PhosphoSitePlus
Y905 Phosphorylation PhosphoSitePlus
K909 Ubiquitination PhosphoSitePlus
T1051 O-Glycosylation GlyGen 28510447, 33465208, 29351928
K1055 Ubiquitination PhosphoSitePlus
K1071 Ubiquitination PhosphoSitePlus
S1115 Phosphorylation PhosphoSitePlus   RLIMS-P 9867875
K1132 Ubiquitination PhosphoSitePlus
K1144 Ubiquitination PhosphoSitePlus
S1149 Phosphorylation PhosphoSitePlus
S1153 Phosphorylation PhosphoSitePlus
K1156 Ubiquitination PhosphoSitePlus
Y1158 Phosphorylation PhosphoSitePlus
K1161 Ubiquitination PhosphoSitePlus
S1162 Phosphorylation PhosphoSitePlus
S1165 Phosphorylation PhosphoSitePlus
T1168 Phosphorylation PhosphoSitePlus
T1181 Phosphorylation PhosphoSitePlus
K1194 Ubiquitination PhosphoSitePlus
K1197 Ubiquitination PhosphoSitePlus
Y1212 Phosphorylation phospho.ELM   PhosphoSitePlus 9182531, 12540962
Site PTM Type PTM Enzyme Score Source PMID
S328 Phosphorylation HPRD 18510355, 18578522
Y1139 Phosphorylation PhosphoSitePlus
T1151 Phosphorylation PhosphoSitePlus
S1152 Phosphorylation PhosphoSitePlus
S1165 Phosphorylation PhosphoSitePlus
S1168 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S328 Phosphorylation HPRD 18510355, 18578522
T1102 Phosphorylation PhosphoSitePlus
K1105 Ubiquitination PhosphoSitePlus
T1132 Phosphorylation HPRD 17081983
T1145 Phosphorylation PhosphoSitePlus
Y1176 Phosphorylation Q05397 (PTK2) , P12931 (SRC) HPRD   PhosphoSitePlus   Signor 9182531, 12540962
T1203 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K1105 N1105 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y1139 C1139 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1165 C1165 Biomuta DOID:1324 / lung cancer [ cosmic ]