Protein Information

Cytoscape View

UniProt AC / UniProt ID P23560 / BDNF_HUMAN
Protein Name Brain-derived neurotrophic factor precursor
Gene Name Name: BDNF
Organism Homo sapiens (Human)

PRO ID PR:P23560
DAG View
PRO Name brain-derived neurotrophic factor (human)
Definition A brain-derived neurotrophic factor that is encoded in the genome of human.
Short Label hBDNF
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P23560 (BDNF) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K50 Ubiquitination PhosphoSitePlus
T62 Phosphorylation PhosphoSitePlus   RLIMS-P 23712400
T62 Phosphorylation O96017 (CHEK2) PhosphoSitePlus 23712400
K85 Acetylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
N121 N-Glycosylation GlyGen   UniProt 19467646, 11152678
T155 Phosphorylation PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T15 Phosphorylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus
Y20 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K50 N50 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]