iPTMnet Report for P23511 (NFYA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P23511 / NFYA_HUMAN
Protein Name Nuclear transcription factor Y subunit alpha
Gene Name Name: NFYA
Organism Homo sapiens (Human)

PRO ID PR:P23511
DAG View
PRO Name nuclear transcription factor Y subunit alpha (human)
Definition A nuclear transcription factor Y subunit alpha that is encoded in the genome of human.
Short Label hNFYA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P23511 (NFYA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S96 O-Glycosylation GlyGen   IEDB 28314751
T98 O-Glycosylation GlyGen 28314751, 34925382
T184 O-Glycosylation GlyGen 23301498, 33214551, 28314751, ...35138101, 29351928, 34019948, 32119511
S188 O-Glycosylation GlyGen 23301498, 33214551, 28314751, ...35138101, 29351928, 34019948, 32119511
T192 O-Glycosylation GlyGen 23301498, 33214551, 28314751, ...35138101, 29351928, 34019948, 32119511
S197 O-Glycosylation GlyGen 23301498, 33214551, 28314751, ...35138101, 29351928, 34019948, 32119511
Y266 Phosphorylation PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
K297 Acetylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
R317 Methylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
S326 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T341 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K284 Acetylation PR:000007102 (EP300) PRO 18815279
K290 Acetylation PR:000007102 (EP300) PRO 18815279
S320 Phosphorylation P24941 (CDK2) HPRD 12857729
S326 Phosphorylation P24941 (CDK2) HPRD 12857729, 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S291 Phosphorylation P24941 (CDK2) HPRD 12857729
S297 Phosphorylation P24941 (CDK2) HPRD 12857729, 18669648, 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000028596 (hNFYA/iso:1/Ac:1) acK284,acK290 PR:000007102 (EP300) PRO 18815279


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S96 F96 Biomuta DOID:184 / bone cancer [ cosmic ]
T98 A98 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T184 A184 Biomuta DOID:1319 / brain cancer [ cosmic ]
R317 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ]
R317 Q317 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T341 S341 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T341 P341 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]