Protein Information

Cytoscape View


UniProt AC / UniProt ID P23470 / PTPRG_HUMAN
Protein Name Receptor-type tyrosine-protein phosphatase gamma precursor
Gene Name Name: PTPRG
Synonyms:PTPG;
Organism Homo sapiens (Human)

PRO ID PR:P23470
DAG View
PRO Name receptor-type tyrosine-protein phosphatase gamma (human)
Definition A receptor-type tyrosine-protein phosphatase gamma that is encoded in the genome of human.
Short Label hPTPRG
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P23470 (PTPRG) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N113 N-Glycosylation UniProt 16335952
Y132 Phosphorylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus
Y419 Phosphorylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus
N444 N-Glycosylation UniProt 16335952
T633 O-Glycosylation PhosphoSitePlus
T640 O-Glycosylation PhosphoSitePlus
T649 O-Glycosylation PhosphoSitePlus
T653 O-Glycosylation PhosphoSitePlus
T656 O-Glycosylation PhosphoSitePlus
T681 Phosphorylation PhosphoSitePlus
T715 O-Glycosylation PhosphoSitePlus
S782 Phosphorylation PhosphoSitePlus
S815 Phosphorylation PhosphoSitePlus
Y880 Phosphorylation PhosphoSitePlus
K902 Ubiquitination PhosphoSitePlus
Y906 Phosphorylation PhosphoSitePlus
Y911 Phosphorylation PhosphoSitePlus
K929 Ubiquitination PhosphoSitePlus
Y1021 Phosphorylation PhosphoSitePlus
Y1023 Phosphorylation PhosphoSitePlus
Y1034 Phosphorylation PhosphoSitePlus
K1083 Ubiquitination PhosphoSitePlus
K1155 Ubiquitination PhosphoSitePlus
Y1164 Phosphorylation PhosphoSitePlus
S1182 Phosphorylation PhosphoSitePlus   UniProt 21406692
K1201 Acetylation PhosphoSitePlus
Y1307 Phosphorylation PhosphoSitePlus
S1409 Phosphorylation PhosphoSitePlus
S1435 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1182 Phosphorylation HPRD 18578522
S1435 Phosphorylation HPRD 19413330, 18578522


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y880 N880 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y880 * Biomuta DOID:3070 / malignant glioma [ cosmic, icgc, tcga ]
Y1164 H1164 Biomuta DOID:11934 / head and neck cancer [ tcga ]