iPTMnet Report for P23470 (PTPRG)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P23470 / PTPRG_HUMAN
Protein Name Receptor-type tyrosine-protein phosphatase gamma precursor
Gene Name Name: PTPRG
Synonyms:PTPG;
Organism Homo sapiens (Human)

PRO ID PR:P23470
DAG View
PRO Name receptor-type tyrosine-protein phosphatase gamma (human)
Definition A receptor-type tyrosine-protein phosphatase gamma that is encoded in the genome of human.
Short Label hPTPRG
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P23470 (PTPRG) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N109 N-Glycosylation GlyGen 24190977
N113 N-Glycosylation GlyGen   UniProt 16335952, 24190977
Y132 Phosphorylation PhosphoSitePlus
N156 N-Glycosylation GlyGen 23090970, 24190977
S320 Phosphorylation PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus
Y419 Phosphorylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus
N444 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 29391424, ...24190977
T514 O-Glycosylation GlyGen 30459171
S561 O-Glycosylation GlyGen 30459171
N619 N-Glycosylation GlyGen 29391424
T633 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T640 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
T649 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T653 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T656 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T681 Phosphorylation PhosphoSitePlus
T715 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
N722 N-Glycosylation GlyGen 29391424
S782 Phosphorylation PhosphoSitePlus
N813 N-Glycosylation GlyGen 29391424
S815 Phosphorylation PhosphoSitePlus
Y880 Phosphorylation PhosphoSitePlus
K902 Ubiquitination PhosphoSitePlus
Y906 Phosphorylation PhosphoSitePlus
Y911 Phosphorylation PhosphoSitePlus
K929 Ubiquitination PhosphoSitePlus
Y1021 Phosphorylation PhosphoSitePlus
Y1023 Phosphorylation PhosphoSitePlus
Y1034 Phosphorylation PhosphoSitePlus
K1083 Ubiquitination PhosphoSitePlus
K1155 Ubiquitination PhosphoSitePlus
Y1164 Phosphorylation PhosphoSitePlus
N1181 N-Glycosylation GlyGen 29391424
S1182 Phosphorylation PhosphoSitePlus   UniProt 21406692
K1201 Acetylation PhosphoSitePlus
N1207 N-Glycosylation GlyGen 29391424
Y1307 Phosphorylation PhosphoSitePlus
S1409 Phosphorylation PhosphoSitePlus
S1435 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1182 Phosphorylation HPRD 18578522
S1435 Phosphorylation HPRD 19413330, 18578522


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N109 I109 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S433 N433 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T514 M514 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
N813 T813 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y880 N880 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y880 * Biomuta DOID:1319 / brain cancer [ cosmic ]
K929 M929 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y1021 H1021 Biomuta [ cosmic ]
Y1164 H1164 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
N1207 D1207 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]