Protein Information

Cytoscape View


UniProt AC / UniProt ID P23109 / AMPD1_HUMAN
Protein Name AMP deaminase 1
Gene Name Name: AMPD1
Organism Homo sapiens (Human)

PRO ID PR:P23109
DAG View
PRO Name AMP deaminase 1 (human)
Definition An AMP deaminase 1 that is encoded in the genome of human.
Short Label hAMPD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P23109 (AMPD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K56 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
K354 Acetylation PhosphoSitePlus
K354 Ubiquitination PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
Y356 Phosphorylation PhosphoSitePlus
T367 Phosphorylation PhosphoSitePlus
K368 Ubiquitination PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
K407 Ubiquitination PhosphoSitePlus
K451 Ubiquitination PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
Y576 Phosphorylation PhosphoSitePlus
Y580 Phosphorylation PhosphoSitePlus
S626 Phosphorylation PhosphoSitePlus
K691 Acetylation PhosphoSitePlus
K732 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K56 E56 Biomuta DOID:2531 / hematologic cancer [ icgc ]
K171 R171 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K186 N186 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S355 Y355 Biomuta DOID:363 / uterine cancer [ tcga ]
T367 I367 Biomuta DOID:5041 / esophageal cancer [ tcga ]
K375 * Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
K407 T407 Biomuta DOID:1909 / melanoma [ cosmic ]